Results 51 to 60 of about 3,290 (193)

Novel therapeutic targets for chronic visceral pain in gastrointestinal disorders

British Journal of Pharmacology, EarlyView.
Chronic visceral pain imposes a major clinical challenge in gastroenterology and beyond, profoundly impacting patients' quality of life. However, limited understanding of its complex, multifaceted pathophysiology, encompassing both peripheral and central mechanisms, continues to impede the development of effective management strategies.
Fleur Veldman, Christopher J. Black, Andrea Shin, Daniel Keszthelyi   +3 more
wiley   +1 more source

Transcranial static magnetic field stimulation - new non-invasive brain stimulation tool

Journal of Physical Fitness and Sports Medicine, 2016
Recent research has shown that the human motor cortex can be modulated by the application of static magnetic fields through the scalp. Transcranial static magnetic field stimulation (tSMS) has since received significant attention as a new non-invasive ...
Hikari Kirimoto, Hiroyuki Tamaki, Hideaki Onishi   +2 more
doaj   +1 more source

FDX1 Depletion Activates CD8+ T Cell Antitumor Immunity by Promoting DMBT1 Secretion in Cuproptosis of Colorectal Cancer

Cancer Science, EarlyView.
Elesclomol‐induced cuproptosis potently activates both innate and adaptive antitumor immunity, especially CD8+ T cell immunity. FDX1 serves as a central regulator of CD8+ T cell functionality through DMBT1 downregulation during cuproptosis in colorectal cancer.
Jieqiong Wu, Zaixi Lian, Mingzhou Li, Xingtu Qin, Xiaoyu Lei, Lihua Yang, Lin Bing, Qiuyue Li, Lingyan Zhou, Zhiyang Ma, Xuemei Xu, Jinghao Huang, Zilong Chen, Lijie Chen, Lingjie Zhang, Zhiyuan Xiao, Xiangyu Jian, Xiaoqin Zhang, Yanqing Ding, Yaping Ye, Li Liang, Hongli Jiao, Shuyang Wang   +22 more
wiley   +1 more source

NIBS-BIDS: an extension to the brain imaging data structure for non-invasive brain stimulation

The Brain Imaging Data Structure (BIDS) is a community standard for organizing and sharing neuroimaging data. Here we present NIBS-BIDS (BEP037), an extension of BIDS for non-invasive brain stimulation (NIBS) data. This specification introduces a dedicated nibs/ datatype with a scalable framework for storing stimulation parameters, modality-specific ...
Bertazzoli, Giacomo, Shevtsov, Oleg, Bulgari, Martina, Fried, Peter, Guidali, Giacomo, Iacovella, Vittorio, Marcantoni, Eleonora, Bergmann, Til Ole, Breuer, Friederike, De Smet, Stefanie, Deng, Zhi-De, Feurra, Matteo, Gau, Remi, Halchenko, Yaroslav, Julio C., Hernandez-Pavon, Holmes, Nicholas P, Hopkins, Amber, Isabella, Silvia, Makarova, Milana, Niso, Guiomar, Oathes, Desmond, Pellegrino, Giovanni, Rotstein, Natalie, Victor H., Souza, Vijayakumar, Suhas, Vinding, Mikkel Christoffer, Kuhn, Taylor, Bortoletto, Marta, Rogasch, Nigel   +28 more
openaire   +4 more sources

Electrical field based dosing improves non-invasive brain stimulation

, 2023
Non-invasive brain stimulation (NIBS) methods, such as transcranial magnetic stimulation (TMS), are invaluable tools to modulate cortical activity and behavior, but high within- and between-subject variability limit their efficacy and reliability.
Kuhnke, P. ; https://orcid.org/, Numssen, O. ; https://orcid.org/, Hartwigsen, G. ; https://orcid.org/, Weise, K. ; https://orcid.org/   +3 more
core   +2 more sources

Coordinated regulation of PIEZO2 by alternative splicing, post‐translational modification, membrane trafficking and protein partners

The Journal of Physiology, EarlyView.
Abstract figure legend Regulatory mechanisms such as alternative splicing, post‐translational modification, membrane trafficking, and protein interactions control channel gating, membrane abundance, and overall activity of PIEZO2. Proper regulation supports PIEZO2‐dependent proprioceptive, somatosensory, nociceptive, pruriceptive and interoceptive ...
Eunice I. Oribamise, Qinglu Li, Mary G. Garry   +2 more
wiley   +1 more source

Roadmap for the use of non-invasive brain stimulation (NIBS) for tinnitus

Brain Imaging and Stimulation
INTRODUCTION: The demand for effective interventions for tinnitus remains high, with low evidence in conventional therapeutic methods and non-invasive brain stimulation (NIBS). NIBS techniques are an important new alternative for the treatment of tinnitus, in different application modalities such as repetitive transcranial magnetic stimulation (rTMS ...
Lázaro Juliano Teixeira, Daniela Regina Sposito Dias Oliva, Catarina Costa Boffino, Lidiane Maria de Brito Macedo Ferreira, Adriana Leico Oda, Lívia Shirahige   +5 more
openaire   +1 more source

Effect of Dual‐Site Non‐Invasive Brain Stimulation on Upper‐Limb Function After Stroke: A Systematic Review and Meta‐Analysis

Brain and Behavior
Background Non‐invasive brain stimulation (NIBS) has attracted significant attention as it has been proven to be effective in facilitating upper limb motor recovery in patients with stroke.
Meng Ren, Jingjing Xu, Wenjing Wang, Lexian Shen, Chaojie Wang, Haoyang Liu, Lu Chen, Chanjing Liu, Yongheng Tang, Jiening Wang, Tiantian Liu   +10 more
doaj   +1 more source

A 3‐Month Follow‐Up Pilot Study on Accelerated Intermittent Theta Burst Stimulation for Bipolar Depression

Bipolar Disorders, Volume 28, Issue 5, August 2026.
ABSTRACT Background Approximately 25% of patients with bipolar disorder are reported to have treatment‐resistant bipolar depression (TRBD). Accelerated intermittent Theta Burst Stimulation (aiTBS) is an innovative form of repetitive transcranial magnetic stimulation (rTMS), delivering bursts of stimulation at theta wave frequencies, which are believed ...
Daan Neuteboom, Urmi Pahladsingh, Martijn C. Steinbach, Marjan C. Ploegaert, Jasper B. Zantvoord, Anja Lok, Lieuwe de Haan, Karel W. F. Scheepstra   +7 more
wiley   +1 more source

The effectiveness of non-invasive brain stimulation in enhancing lower extremity function in children with spastic cerebral palsy: Protocol for a systematic review and meta-analysis

MethodsX
Non-invasive brain stimulation (NIBS11 Non-invasive brain stimulation.) techniques have emerged as a promising non-pharmacological adjunct to neurorehabilitation.
Clàudia Arumí-Trujillo, Francisco José Verdejo-Amengual, Oriol Martínez-Navarro, Jord J.T. Vink, Fran Valenzuela-Pascual   +4 more
doaj   +1 more source