Results 241 to 250 of about 10,431,045 (283)

Chiral Nanoparticles Suppress Inflammatory Infiltration to Promote Extracellular Matrix Remodeling for Ectopia Lentis Therapy

Advanced Science, EarlyView.
L‐cysteine‐configured chiral polyurethane nanoparticles suppress ocular inflammation and reduce extracellular matrix (ECM) degradation in ectopia lentis by regulating macrophages polarization and inhibiting nuclear factor kappa B signaling pathway. By promoting zonular fiber‐associated protein restoration and tissue repair, this minimally invasive ...
Yinuo Wen, Yan Yang, Haihan Gao, Yan Liu, Xinyue Wang, Linghao Song, Ruohong Li, Ao Miao, Jie Xu, Zhennan Zhao, Dan Li, Shenjie Peng, Linzhao Li, Min Zhang, Yonghang Liu, Liren Wang, Tianhui Chen, Yongxiang Jiang   +17 more
wiley   +1 more source

Liquid Chromatography-Tandem Mass Spectrometry Quantification of Diet-Derived CYP2D6 Biomarkers for Clinical Phenotyping in Japanese Subjects. [PDF]

Clin Transl Sci
Kumondai M, Hayashi N, Matsumoto Y, Ebata A, Sato M, Harada-Shoji N, Tada H, Miyashita M, Ishida T, Maekawa M, Tomioka Y, Mano N.   +11 more
europepmc   +1 more source

ROS Self‐Supply Nanoplatform Based on Fenton Catalyst for Chemodynamic and Immunotherapy: Reprogramming Cold Tumor Into Hot Tumor in Cancer Treatment

Advanced Science, EarlyView.
A multifunctional HA‐conjugated nanoplatform (HA‐PGMC) integrates CuO2, glucose oxidase, and mil‐100 to enable cascade catalytic ROS generation in tumor microenvironments. This self‐supplying ROS strategy induces immunogenic cell death, reprograms “cold” tumors into “hot” ones, and synergizes with PD‐L1 blockade, achieving potent chemodynamic ...
Man Lung Lee, Jack Chun Hin Chen, Wai Wing Cheng, Kwan Yee Lau, Hiu Yee Kwan, Ngar‐Yun Ellen Poon, Hung‐Wing Li   +6 more
wiley   +1 more source

Technological Advances in Molecular Diagnostic Methods for Hereditary Diseases in Preconception and Prenatal Settings. [PDF]

Curr Issues Mol Biol
Kong D, Zhao J, Diao H, Qiu S, Peng Y, Liu T.   +5 more
europepmc   +1 more source

Lactiplantibacillus Plantarum GUANKE Alleviates Allergic Asthma by Restricting Monocyte‐to‐DC Differentiation Via Microbiota‐Associated IAA

Advanced Science, EarlyView.
Lactiplantibacillus plantarum GUANKE remodels the indigenous gut microbiota and is associated with microbiota‐dependent restoration of circulating IAA. IAA treatment attenuates JAK3‐STAT3 and Jag1‐Notch4‐Hey1 signaling and reduces CX3CR1+Ly6C− monocytic precursor generation and pulmonary CD11b+ DC accumulation, together with reduced Th2 inflammation ...
Yujia He, Jielan Mi, Zhiping Zhao, Xiao Zhang, Zhihan Yang, Kun Yue, Yuanming Huang, Liqiong Song, Xiaoting Wen, Jianguo Xu, Zhihong Ren   +10 more
wiley   +1 more source

Redox imbalance in infertility and assisted reproduction: biomarkers, mechanisms, multi-omics integration, and personalised therapeutic strategies. [PDF]

Front Med (Lausanne)
Peramo B, Upadhyay D, Bouhafs L, Alsafar H.   +3 more
europepmc   +1 more source

A Non-Invasive Pathogen‑Responsive RUBY Reporter Enables Visible Monitoring of <i>PR1</i> Activation. [PDF]

MicroPubl Biol
McMullan LO, Taylor JS, Hanlon R, Harris AT, Shuman JL, Schmale Iii DG, Bargmann BOR.   +6 more
europepmc   +1 more source

Risk Recognition and Phenotyping in Cardiac and Vascular Diseases. [PDF]

Biomedicines
Barnaba I, Massari F, Scicchitano P.
europepmc   +1 more source

Physiological Phenotypes in Comatose ICU Patients: A Retrospective Multidimensional Analysis. [PDF]

Diagnostics (Basel)
Bogdan PM, Pleșea-Condratovici A, Bogdan-Goroftei RE, Duceac LD, Armencia AO, Dabija MG, Salim C, Dabija VA, Nicolcescu P, Cristescu-Budală CL, Barbu ER, Calin AM.   +11 more
europepmc   +1 more source

Prenatal diagnosis – where do we go from here? [PDF]

Med Genet
Fauth C, Verheyen S.
europepmc   +1 more source