Results 81 to 90 of about 42,025 (277)

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Early Competitive Effects of Common Ragweed (Ambrosia artemisiifolia L.) on Oilseed Rape (Brassica napus L.) Revealed by Non-Invasive Stress Indicators

Agriculture
Climate change reshapes crop–weed interactions and challenges the cultivation of oilseed rape (Brassica napus L.). Common ragweed (Ambrosia artemisiifolia L.) strongly suppresses early crop development, increases stress sensitivity and leads to yield ...
Bence Knolmajer, Richárd Hoffmann, Róbert Szilágyi, Bettina Frauholcz, Gabriella Kazinczi, Ildikó Jócsák   +5 more
doaj   +1 more source

Writing biology with mutant mice: the monstrous potential of post genomic life [PDF]

, 2011
Social scientific accounts identified in the biological grammars of early genomics a monstrous reductionism, ‘an example of brute life, the minimalist essence of things’ (Rabinow, 1996, p. 89).
Davies, GF
core  

Chemical markers for rumen methanogens and methanogenesis [PDF]

, 2013
Peer reviewedPublisher ...
Bessa, Bhagwat, Brulc, C.A. McCartney, Casto Montoya, Chen, Chilliard, Dehareng, Dehority, Dewhurst, Dewhurst, Diedrich, Dijkstra, Ding, Fievez, Firkins, Frey, Fritze, Gill, Gill, Gu, Guo, Hegarty, Hildenbrand, Hook, Hopmans, Huguet, I.D. Bull, Janssen, Jenkins, Kim, Koga, Koga, Lee, Leng, Liu, Mao, Mathai, McCartney, McGeough, Mohammed, Morgavi, Mosoni, Odongo, Pancost, Pei, Pinares-Patiño, Polidori, R.J. Dewhurst, Schouten, Schouten, Sharp, Shimada, Shin, Shingfield, Stouthamer, Thauer, Tymensen, Valentine, Vlaeminck, Vlaeminck, Weijers, Zhou, Zhou   +63 more
core   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

A Critical Review on ‘Current Status and Future Implications of Advanced Phenotyping Systems for Monitoring of Agricultural Crops’

Turkish Journal of Agricultural Engineering Research
Phenotyping systems propels the growth of modern agriculture, driving innovations in plant breeding, crop management, precise application of resources and smart agriculture. This review provides a comprehensive analysis of phenotyping systems, exploring
Rizwan Ul Zama BANDAY, Mohammad MUZAMIL, Danish GUL, Seemi LOHANI, Sehreen RASOOL, Kezia RAJAN, Muzamil HAMID   +6 more
doaj   +1 more source

Non‐invasive prediction of genotype positive–phenotype negative in hypertrophic cardiomyopathy by 3D modern shape analysis [PDF]

Experimental Physiology, 2019
New Findings What is the central question of this study? Can impaired deformational indicators for genotype positive for hypertrophic cardiomyopathy in subjects that do not exhibit a left‐ventricular wall hypertrophy condition (G+LVH−) be determined using non‐invasive 3D echocardiography? What is the main finding and its importance?
Piras P., Torromeo C., Evangelista A., Esposito G., Nardinocchi P., Teresi L., Madeo A., Re F., Chialastri C., Schiariti M., Varano V., Puddu P. E.   +11 more
openaire   +2 more sources

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

Molecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller, Susanne Ebner, Carmen Haselrieder, Julia K. Günther, Astrid Drasche, Sophie Strich, Chiara Volani, Andrea Medici, Aleksandar Nikolajevic, Alex Deltedesco, Johannes E. Sigmund, Michael J. Blumer, Martin Hermann, Johanna Vanacker, Gerald Brandacher, Eduard Stefan, Omar Torres‐Quesada, Jakob Troppmair   +17 more
wiley   +1 more source

A Review on the Application of Natural Computing in Environmental Informatics [PDF]

, 2018
Natural computing offers new opportunities to understand, model and analyze the complexity of the physical and human-created environment. This paper examines the application of natural computing in environmental informatics, by investigating related work
Kamilaris, Andreas
core   +2 more sources

Redox modulation and non-invasive evaluation of phenotypic adaptation of Escherichia coli Biofilm

International Journal of Electrochemical Science, 2010
Redox condition is a critical determinant of the metabolism of microbial biofilm. In this study, redox control of Escherichia coli biofilm adaptation in anaerobic chamber of electrochemical quartz crystal microbalance was performed to investigate the relationship between biomass yield and redox adapted metabolism.
Xie, Xuan-Hui, Li, Erin Lin, Tang, Zi Kang   +2 more
openaire   +1 more source