Results 91 to 100 of about 12,655,449 (158)

Cost-effectiveness of prenatal screening and diagnostic strategies for Down syndrome: A microsimulation modeling analysis.

PLoS ONE, 2019
OBJECTIVES:Down syndrome (DS) is the most frequently occurring fetal chromosomal abnormality and different prenatal screening strategies are used for determining risk of DS worldwide.
Wei Zhang, Tima Mohammadi, Julie Sou, Aslam H Anis   +3 more
doaj   +1 more source

A Fetal Fraction Optimized 106-Plex Digital PCR Assay for Non-Invasive Prenatal Testing of Fetal Trisomy

Diagnostics
Background/Objectives: Non-invasive prenatal testing (NIPT) for fetal aneuploidy requires accurate trisomy detection together with reliable fetal fraction assessment.
Songchang Chen, Xiaorui Luan, Xianling Cao, Cong Liu, Li Zhang, Wu Shang, Yiliang Zhang, Zhijie Yang, Chenming Xu   +8 more
doaj   +1 more source

Performance of cell free DNA as a screening tool based on the results of first trimester screening

Molecular Cytogenetics
The advent of non-invasive prenatal testing (NIPT) in the screening of fetal abnormalities has optimized prenatal care and decreased the rate of invasive diagnostic tests. In this retrospective descriptive study, we began with 1874 singleton pregnancies.
Mahtab Motevasselian, Mohammad Amin Omrani, Soraya Saleh Gargari, Sarang Younesi, Mohammad Mahdi Taheri Amin, Pourandokht Saadati, Soudabeh Jamali, Mohammad-Hossein Modarresi, Shahram Savad, Majid Rahmani, Saloomeh Amidi, Saeed Delshad, Fariba Navidpour, Samira Chagheri, Yalda Mohammadi, Sheyda Khalilian, Solat Eslami, Soudeh Ghafouri-Fard   +17 more
doaj   +1 more source

Non-invasive prenatal testing for fetal chromosome abnormalities: review of clinical and ethical issues

, 2016
Jean Gekas,1,2 Sylvie Langlois,3 Vardit Ravitsky,4 François Audibert,5 David Gradus van den Berg,6 Hazar Haidar,4 François Rousseau2,7 1Prenatal Diagnosis Unit, Department of Medical Genetics and Pediatrics, Faculty of Medicine, Universit ...
Haidar H, Ravitsky V, Audibert F, Rousseau F, Langlois S, Gekas J, van den Berg DG   +6 more
core  

TRIDENT-2: National Implementation of Genome-wide Non-invasive Prenatal Testing as a First-Tier Screening Test in the Netherlands

, 2019
The Netherlands launched a nationwide implementation study on non-invasive prenatal testing (NIPT) as a first-tier test offered to all pregnant women. This started on April 1, 2017 as the TRIDENT-2 study, licensed by the Dutch Ministry of Health.
The Dutch NIPT Consortium
core  

Non-invasive prenatal cell-free fetal DNA testing for down syndrome and other chromosomal abnormalities

Zdravniški Vestnik, 2015
Background: Chorionic villus sampling and amniocentesis as definitive diagnostic procedures represent a gold standard for prenatal diagnosis of chromosomal abnormalities.
Darija Strah, Petra Ovniček, Janez Bernik   +2 more
doaj  

Budget impact of incorporating non-invasive prenatal testing in prenatal screening for Down syndrome in Turkey

, 2019
Objectives: To provide information to the government about the budget impact of implementing non-invasive prenatal testing (NIPT) into prenatal screening strategies to detect Down syndrome (DS) in singleton pregnancies in Turkey; the likely costs or ...
Cakar, Mehmet, TARI KASNAKOĞLU, BERNA, ÖRGÜL, GÖKÇEN, BEKSAÇ, MEHMET SİNAN, ÖKEM, ZEYNEP GÜLDEM   +4 more
core   +1 more source

Case Report: A family with X-linked ichthyosis identified by secondary findings of non-invasive prenatal testing

Frontiers in Medicine
We report a family with X-linked ichthyosis (XLI), in which the non-invasive prenatal testing (NIPT) results from the pregnant woman revealed a deletion of approximately 2 Mb at Xp22.31, confirmed by chromosome microarray analysis. This deletion includes
Shuzhen Li, Fuxin Chen, Fuxin Chen, Lihua Li, Lihua Li, Miaolian Zhang, Miaolian Zhang, Huahua Li, Huahua Li, Suihua Feng, Suihua Feng, Xiaohong Ruan, Xiaohong Ruan, Qiang Zhao, Qiang Zhao   +14 more
doaj   +1 more source

Patient experience with non-invasive prenatal testing (NIPT) as a primary screen for aneuploidy in the Netherlands. [PDF]

BMC Pregnancy Childbirth, 2022
Kristalijn SA, White K, Eerbeek D, Kostenko E, Grati FR, Bilardo CM.   +5 more
europepmc   +1 more source

Positive Attitudes towards Non-Invasive Prenatal Testing (NIPT) in a Swedish Cohort of 1,003 Pregnant Women

, 2016
OBJECTIVE: The clinical utilization of non-invasive prenatal testing (NIPT) for identification of fetal aneuploidies is expanding worldwide. The aim of this study was to gain an increased understanding of pregnant women's awareness, attitudes ...
Josephine Wincent, Wincent, Josephine, Erik Iwarsson (507949), Ellika Sahlin, Susanne Georgsson, Nordenskjöld, Magnus, Josephine Wincent (2794045), Iwarsson, Erik, Ellika Sahlin (507944), Peter Gustavsson, Magnus Nordenskjöld (118610), Magnus Nordenskjöld, Erik Iwarsson, Georgsson, Susanne,, Sahlin, Ellika, Susanne Georgsson (2794042), Gustavsson, Peter, Georgsson, Susanne, Peter Gustavsson (118726)   +18 more
core   +1 more source