Results 51 to 60 of about 8,134 (208)

An Economic Analysis of Cell-Free DNA Non-Invasive Prenatal Testing in the US General Pregnancy Population. [PDF]

PLoS ONE, 2015
Analyze the economic value of replacing conventional fetal aneuploidy screening approaches with non-invasive prenatal testing (NIPT) in the general pregnancy population.Using decision-analysis modeling, we compared conventional screening to NIPT with ...
Peter Benn, Kirsten J Curnow, Steven Chapman, Steven N Michalopoulos, John Hornberger, Matthew Rabinowitz   +5 more
doaj   +1 more source

For your interest?:The ethical acceptability of using non-invasive prenatal testing to test 'purely for information' [PDF]

, 2014
Non-invasive prenatal testing (NIPT) is an emerging form of prenatal genetic testing that provides information about the genetic constitution of a foetus without the risk of pregnancy loss as a direct result of the test procedure.
Clarke, Angus J, Deans, Zuzana, Newson, Ainsley J   +2 more
core   +3 more sources

Uptake, outcomes, and costs of implementing non-invasive prenatal testing for Down's syndrome into NHS maternity care: prospective cohort study in eight diverse maternity units. [PDF]

, 2016
OBJECTIVE:  To investigate the benefits and costs of implementing non-invasive prenatal testing (NIPT) for Down's syndrome into the NHS maternity care pathway. DESIGN:  Prospective cohort study.
Cameron, L, Chitty, LS, Daley, R, Fisher, J, Hill, M, Howarth, A, Jenkins, L, Kroese, M, Lewis, C, Mason, S, McEwan, A, McKay, F, Morris, S, Verhoef, TI, Wright, D   +14 more
core   +1 more source

Non‐invasive prenatal testing (NIPT): Combination of copy number variant and gene analyses using an “in‐house” target enrichment next generation sequencing—Solution for non‐centralized NIPT laboratory?

Prenatal Diagnosis, 2023
Recent studies have integrated copy number variant (CNV) and gene analysis using target enrichment. Here, we transferred this concept to our routine genetics laboratory, which is not linked to centralized non‐invasive prenatal testing (NIPT) facilities.
Lucie Faldynová, S. Walczysková, Dita Černá, Monika Kudrejová, Š. Hilscherová, Romana Kaniová, Simona Širůčková   +6 more
semanticscholar   +1 more source

Review of: "Non-Invasive Prenatal Testing (NIPT) for Aneuploidy in a Setting with a High Consanguineous Rate – A Retrospective Cohort Review of 1,153 Cases" [PDF]

, 2023
J. Čítek
  +10 more sources

Whole genome non-invasive prenatal testing in prenatal screening algorithm: clinical experience from 12,700 pregnancies

BMC Pregnancy and Childbirth, 2022
Background A fast adoption of a non–invasive prenatal testing (NIPT) in clinical practice is a global tendency last years. Firstly, in Russia according a new regulation it was possible to perform a widescale testing of pregnant women in chromosomal ...
Elena E. Baranova, Olesya V. Sagaydak, Alexandra M. Galaktionova, Ekaterina S. Kuznetsova, Madina T. Kaplanova, Maria V. Makarova, Maxim S. Belenikin, Anton S. Olenev, Ekaterina N. Songolova   +8 more
doaj   +1 more source

Discordant performances of non-invasive prenatal testing for foetal trisomy 21 screening in subgroups of pregnancies

Journal of Obstetrics and Gynaecology, 2023
Background Non-invasive prenatal testing (NIPT) has been widely adopted as an approach for foetal aneuploidy screening. This study was to evaluate the performance of NIPT for foetal T21 detection in subgroups of pregnancies and the correlation between Z ...
Feng Suo, Yi Wang, Na Wang, Yawen Wang, Mingming Liao, Jingjing Wang, Chuanxia Wang, Yan Zhang, Man Zhang, Chu Zhang, Maosheng Gu, Lingshan Gou   +11 more
doaj   +1 more source

Abnormal plasma DNA profiles in early ovarian cancer using a non-invasive prenatal testing platform: Implications for cancer screening [PDF]

, 2016
Background: Non-invasive prenatal testing (NIPT) identifies fetal aneuploidy by sequencing cell-free DNA in the maternal plasma. Pre-symptomatic maternal malignancies have been incidentally detected during NIPT based on abnormal genomic profiles.
Cohen, P, Flowers, N, Hannan, N, Hui, L, Pertile, M, Tong, S   +5 more
core   +2 more sources

Enlarged NT (≥3.5 mm) in the first trimester - Not all chromosome aberrations can be detected by NIPT [PDF]

, 2016
__Background:__ Since non-invasive prenatal testing (NIPT) in maternal blood became available, we evaluated which chromosome aberrations found in our cohort of fetuses with an enlarged NT in the first trimester of pregnancy (tested with SNP microarray ...
Bos, M.J. (Marnix), Diderich, K.E.M. (Karin), Galjaard, R-J.H. (Robert-Jan), Go, A.T.J.I. (Attie), Govaerts, L.C. (Lutgarde), Joosten, A-M.S (Marieke), Knapen, M.F.C.M. (Maarten), Koningen, M. (Mieke), Looye-Bruinsma, G.A.G. (Gerda), Srebniak, M.I. (Malgorzata), Van Opstal, A.R.M. (Diane), Wit, M.C. (Merel) de   +11 more
core   +1 more source

Investigational Management for a Positive NIPT Result - Case Report [PDF]

Modern Medicine
Non-invasive prenatal testing (NIPT), since its introduction in 2011, has revolutionized prenatal screening, becoming widely used globally and replacing traditional screening methods in developed countries.
Elena Evelina STOICA, Laurentiu Camil BOHILTEA, Delia-Maria Gradinaru-FOMETESCU, Monica Mihaela CIRSTOIU   +3 more
doaj   +1 more source