Results 91 to 100 of about 2,228,362 (259)
, 2012 The aim of this paper is to explore the possibilities of Conley index techniques in the study of heteroclinic connections between finite and infinite invariant sets.
Hell, Juliette
core
Molecular bases of circadian magnesium rhythms across eukaryotes
FEBS Letters, EarlyView.Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley +1 more source
Non-isolating 2-bondage in graphs
Journal of the Mathematical Society of Japan, 2013 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire +2 more sources
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
FEBS Letters, EarlyView.Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
Invariants of non-isolated singularities of hypersurfaces
Journal of Pure and Applied AlgebraIn this paper we generalize some results by Siersma, Pellikaan, and de Jong regarding morsifications of singular hypersurfaces whose singular locus is a smooth curve, and present some applications to the study of Yomdin-type isolated singularities. In order to prove these results, we discuss the transversal discriminant of such singularities and how it
openaire +2 more sources
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
FEBS Letters, EarlyView.The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
FEBS Letters, EarlyView.This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Non-isolated types in stable theories
Annals of Pure and Applied Logic, 2007 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire +1 more source
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
FEBS Letters, EarlyView.Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
NON CLASSIC 21 HYDROXYLASE DEFICIENT ADRENAL HYPERPLASIA IN PATIENTS WITH ISOLATED PRECOCIOUS PUBARCHE [PDF]
Acta Medica Iranica, 2003 Precocious Pubarche (PP) is most often a benign condition secondary to the early appearance of adrenarche. However, PP may be a manifestation of mild errors of steroidogenesis in particular non classic 21 hydroxylase deficiency (NC210HD).
H. Moayeri +1 more
doaj +1 more source