Results 111 to 120 of about 2,265,753 (326)

Convergence and Convergence Rate of Stochastic Gradient Search in the Case of Multiple and Non-Isolated Extrema

, 2013
The asymptotic behavior of stochastic gradient algorithms is studied. Relying on results from differential geometry (Lojasiewicz gradient inequality), the single limit-point convergence of the algorithm iterates is demonstrated and relatively tight ...
Tadic, Vladislav B.
core  

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Biofilm Production among Extended Spectrum Beta Lactamase Producing and non-Producing Escherichia coli Isolated from Clinical Specimen

, 2022
Beena Shrestha, Anup Bastola, Pawana Pandey, Shova Shrestha   +3 more
openalex   +2 more sources

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Decision letter for "Non-isolated enhanced gain of DC-DC converter for DC micro-grid applications"

, 2020

openalex   +1 more source

Selective Alpha7 Nicotinic Receptor Agonist Increases Cardiac Function in Isolated Mouse Hearts by a Non-Nicotinic Mechanism [PDF]

, 2015
Cyrus Takahashi, Pooja S. Jagadish, Ashwin Jagadish, John P. Toscano, Nazareno Paolocci, Donald B. Hoover   +5 more
openalex   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Isolated non diabetic renal disease in diabetic patients: A moroccan report

Saudi Journal of Kidney Diseases and Transplantation, 2010
The occurrence of non-diabetic renal disease (NDRD) in diabetic patients is well established, with different frequencies from all around the world. We report 13 cases of isolated NDRD in diabetic patients diagnosed in our unit and present our biopsy ...
Haddiya Intissar, Hamzaoui Hakim, Hamany Zitouna, Radoui Aicha, Rhou Hakima, Benamar Loubna, Bayahia Rabia, Ouzeddoun Naima   +7 more
doaj  

Treatment of unilateral cervical facet fractures without evidence of dislocation or subluxation: a narrative review and proposed treatment algorithm

EFORT Open Reviews
Isolated cervical spine facet fractures are often overlooked. The primary imaging modality for diagnosing these injuries is a computed tomography scan.
Juan Ignacio Cirillo, Guillermo A Ricciardi, Facundo Lisandro Alvarez Lemos, Alfredo Guiroy, Ratko Yurac, Klaus Schnake   +5 more
doaj   +1 more source