Results 41 to 50 of about 13,127,584 (298)

Heterotropic regulation and negative homotropic cooperativity

FEBS Open Bio, EarlyView.
We identified a structural module common to some proteins that couple negative cooperativity with heterotropic regulation, two features that rarely coexist. These proteins are ring‐like and present an ordered asymmetry whereby noncontacting subunits are symmetric, and their tertiary structure differs from that of contacting subunits.
Veronica Morea, Francesco Angelucci, Federica Arnesano, Gianmarco Pascarella, Patrizio Di Micco, Andrea Bellelli   +5 more
wiley   +1 more source

Development of An Integrated Circuits for Non-Isolated DC-DC Converters

, 2022
Non-isolated buck circuit, boost circuit, buck/boost circuit and Cuk circuit are important basic circuits of DC-DC converters. An integrated circuit of these four circuits has been developed and presented in this paper. The integrated circuit was developed according to the rules of thumb.
Wen-chih Yang, Kuan-yi Lee, Jhih-yun Tien, Lo-tung Chen   +3 more
openaire   +2 more sources

Spatial and Volumetric Characteristics of Glioblastoma: Associations With Clinical Presentation and Survival

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective We aim to comprehensively analyze how regional tumor and edema characteristics are associated with clinical presentations and survival outcomes in a large cohort of glioblastoma patients. Methods Patients with IDH‐wildtype glioblastoma who received brain MRI from 2010 to 2023 were included.
Daniel J. Zhou, Marc Jaskir, Julian Gal, Yombe Fonkeu, Christos Davatzikos, MacLean P. Nasrallah, Jose Garcia, Rubo Xing, Stephen J. Bagley, Arati Desai, Richard E. Phillips, Steven Tobochnik, Colin A. Ellis, James J. Gugger, Nishant Sinha, Joel M. Stein, Kathryn A. Davis   +16 more
wiley   +1 more source

Analysis and implementation of high‐gain non‐isolated DC–DC boost converter [PDF]

IET Power Electronics, 2017
High step‐up DC–DC converters are increasingly required in many industrial applications. Conventional topologies operate at extreme duty cycle, high‐semiconductor voltage stress, switching loss, and diode reverse recovery problems. This study presents a new non‐isolated high gain, boost converter operating with a modest duty cycle ...
Muhammad M, Armstrong M, Elgendy MA
openaire   +2 more sources

State-of-the-Art DC-DC Converters for Satellite Applications: A Comprehensive Review

Aerospace
Future manned and deep space missions require an Electrical Power System (EPS) that can deliver high power while overcoming challenges like weight and volume constraints and the harsh space environment.
Reshma Ravindran, Ahmed M. Massoud
doaj   +1 more source

A Transformerless Non-Isolated Multi-Port DC–DC Converter for Hybrid Energy Applications

IEEE Access, 2023
This paper presents a novel high-gain non-isolated Four Port DC-DC converter (FPC) topology for hybrid energy applications. The proposed four-port dc-dc converter interfaces four power ports of three input ports and one output port. High output voltage gain, minimized component count, and high efficiency are the advantages of the proposed converter ...
R. Aravind 0002, Bharatiraja Chokkalingam, Lucian Mihet-Popa   +2 more
openaire   +2 more sources

Characterizing Cutaneous α‐Synuclein Deposition and Seeding Activity in Parkinson's Disease Subtypes

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Cutaneous phosphorylated α‐synuclein (p‐syn) and α‐synuclein seeding activity are promising biomarkers for Parkinson's disease (PD), but their clinical value remains uncertain due to disease heterogeneity. This study evaluates these two biomarkers in PD patients to inform phenotype‐specific diagnosis and disease severity assessment ...
Yuting Jin, Tianyuan Yang, Minglei Liu, Haiyang Luo, Jing Yuan, Ke Zhang, Xinsheng Han, Jing Yang, Yuming Xu   +8 more
wiley   +1 more source

Deep Learning Pose Estimation for Phenotyping of Co‐Occurring Hyperkinetic Movement Disorders

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore whether routine outpatient video combined with deep learning‐based pose estimation and clinically interpretable kinematic features can support multi‐label phenotyping of co‐occurring hyperkinetic movement disorders (HMDs).
Laura Cif, Diane Demailly, Gabriella A. Horvàth, Juan Dario Ortigoza Escobar, Nathalie Dorison, Mayté Castro Jiménez, Cécile A. Hubsch, Thomas Wirth, Gun‐Marie Hariz, Sophie Huby, Morgan Dornadic, Zohra Souei, Muhammad Mushhood Ur Rehman, Simone Hemm, Mehdi Boulaymen, Eduardo M. Moraud, Jocelyne Bloch, Xavier Vasques   +17 more
wiley   +1 more source

The Association of Amyloid‐β and Tau With Synaptic Dysfunction in Alzheimer's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To clarify the relative contributions of amyloid and tau to synaptic dysfunction in Alzheimer's disease (AD). Methods We included 109 cognitively unimpaired and impaired individuals from the Geneva Memory Center with available CSF synaptic biomarkers (neurogranin, SNAP‐25, GAP‐43). Participants were stratified according to amyloid (A)
Fausto Roveta, Augusto J. Mendes, Valentina Garibotto, Cecilia Boccalini, Aurelien Lathuiliere, Innocenzo Rainero, Elisa Rubino, Henrik Zetterberg, Nicholas J. Ashton, Federica Ribaldi, Giovanni B. Frisoni, for the Alzheimer's Disease Neuroimaging Initiative   +11 more
wiley   +1 more source

Bidirectional DC-DC Converter Topologies for Hybrid Energy Storage Systems in Electric Vehicles: A Comprehensive Review

Energies
Electric Vehicles (EV) significantly contribute to reducing carbon emissions and promoting sustainable transportation. Among EV technologies, hybrid energy storage systems (HESS), which combine fuel cells, power batteries, and supercapacitors, have been ...
Yan Tong, Issam Salhi, Qin Wang, Gang Lu, Shengyu Wu   +4 more
doaj   +1 more source