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Langerin is a type II transmembrane C-type lectin associated with the formation of Birbeck granules in Langerhans cells. Langerin is a highly selective marker for Langerhans cells and the lesional cells of Langerhans cell histiocytosis. Although Langerin protein expression in Langerhans cell histiocytosis has been previously documented, the specificity
Sean K, Lau +2 more
semanticscholar +4 more sources
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Primary cerebral non-Langerhans cell histiocytosis: MRI and differential diagnosis
Neuroradiology, 2002We report a young woman with primary cerebral non-Langerhans cell histiocytosis of the juvenile xanthogranuloma family. The clinical course was complicated by extensive infiltration of cranial nerves and meninges and epi- and intramedullary spinal dissemination.
U, Ernemann +5 more
exaly +5 more sources
Journal of the American Academy of Dermatology, 2009
The advent of electron microscopy and immunohistochemical stains allowed for reclassification of the histiocytoses based on the predominant cell in the infiltrate. Although the current schema simplicity provides a good foundation, some patients display overlapping clinical and immunohistochemical features that defy classification.
Elizabeth K, Satter +2 more
exaly +5 more sources
The advent of electron microscopy and immunohistochemical stains allowed for reclassification of the histiocytoses based on the predominant cell in the infiltrate. Although the current schema simplicity provides a good foundation, some patients display overlapping clinical and immunohistochemical features that defy classification.
Elizabeth K, Satter +2 more
exaly +5 more sources
Non-Langerhans cell histiocytosis associated with lymphocyte-predominant Hodgkin's disease
We report a 74-year-old man who presented with a rash on the trunk showing clinical and histological features of non-Langerhans cell histiocytosis. Two years after presentation he developed weight loss, lymphadenopathy and hepatosplenomegaly; a diagnosis of lymphocyte-predominant Hodgkin's disease was made on lymph node biopsy.
null Ibbotson +3 more
semanticscholar +6 more sources
Non-Langerhans cell histiocytosis
Acta Neurologica Belgica, 2016A 34-year-old man complained of seizures, headache and reduced visual acuity for a month. Physical examination revealed intracranial hypertension. CSF showed high opening pressure, increase of protein (121 mg/dl) and 26 leukocytes per mm, 94 % of which were lymphomononuclear cells, with cytoplasmic and nuclear atypia.
Lívia Nathália Alaite Silveira +2 more
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A Child with Both Langerhans and Non‐Langerhans Cell Histiocytosis
Pediatric Dermatology, 2002Abstract: The histiocytic syndromes consist of a group of disorders that share in common the proliferation of cells of the monocytic/macrophage lineage. It has been conventional to divide the histiocytoses into two separate groups: Langerhans cell histiocytosis (LCH) and non‐LCH.
Ayelet, Shani-Adir +3 more
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Erdheim- Chester Disease (Non-Langerhans Cell Histiocytosis)
Journal of Cancer Research Reviews & Reports52 years old female with recurrent admission for myalgias, inflammatory arthritis, rash around the eyes and abdomen (A, B). Routine blood tests were either normal or negative apart from low C4 level. Pan CT of the body was unremarkable.
Adel Ekladious, Yousef Gulnaz
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Progressive nodular histiocytosis – rare variant of cutaneous non‐Langerhans cell histiocytosis
JDDG: Journal der Deutschen Dermatologischen Gesellschaft, 2006SummaryProgressive nodular histiocytosis is an extremely rare skin disease is clinically characterized by the coincidence of two distinct lesions, namely, superficial xanthomatous papules up to 5 mm and deep nodules and tumors 1–3 cm. Histologically the nodules represent spindle cell xanthogranulomas.
Matthias, Lüftl +3 more
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Congenital self-healing non-Langerhans cell histiocytosis
European Journal of Pediatrics, 1988Clinical, morphological, ultrastructural and immunological studies were performed in a case of congenital self-healing non-Langerhans cell histiocytosis. The patient showed several aspects that have not been published before: a large nodule in the vulvar region, vesiculobullous elements and pneumonia (asymptomatic). The relationship of the vesicles and
A P, Oranje +3 more
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