Results 61 to 70 of about 33,351,846 (252)
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi +5 more
wiley +1 more source
Organoids in pediatric cancer research
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
The widespread brittle failure of welded beam-to-column connections caused by the 1994 Northridge and 1995 Kobe earthquakes highlighted the need for retrofitting measures effective in reducing the strength demand imposed on connections under cyclic ...
Daniel Tomas Naughton +3 more
doaj +1 more source
The method of integration of dynamical systems admitting non-linear superpositions is applied to four-dimensional non-linear dynamical systems. All four-dimensional dynamical systems admitting non-linear superpositions with four-dimensional Vessiot ...
Ibragimov, Nail, +1 more
core +1 more source
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Fourier Analysis and Synthesis for a Mildly Non-Linear Quantizer
This Unclassified Report is a compilation, extended with certain new results, of those parts of NLR 6918/96 (A.J.E.M. Janssen), NLR 6923/96 (M.T. Looijer), NLTN 423/96 (A.J.E.M. Janssen), NLR 7006 (R. de Vries, A.J.E.M. Janssen) and NLR 7043/98 (A.J.E.M.
Non-linear Quantizer, A.J.E.M. Janssen
core
Calpain small subunit homodimerization is robust and calcium‐independent
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Non-linear predictive control for manufacturing and robotic applications [PDF]
The paper discusses predictive control algorithms in the context of applications to robotics and manufacturing systems. Special features of such systems, as compared to traditional process control applications, require that the algorithms are capable of ...
Grimble, M.J., Ordys, A.W.
core +3 more sources
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Background: Individuals with spinal cord injury (SCI) lose their abilities to stand. The effectiveness of compensating strategies such as the use of various orthosis is studied by stability analysis.
Hamidreza Kargar, Vahid Zolaktaf
doaj

