Results 81 to 90 of about 2,447,517 (340)

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

Load frequency control of power systems with non‐linearities

IET Generation, Transmission & Distribution, 2017
Load frequency control (LFC) for power systems with governor deadband (GDB) and generation rate constraint (GRC) non‐linearities is discussed in this study, with the objective to add anti‐windup schemes for any designed LFC controller, so that the stability and performance of the existing LFC controller can be retained when there are non‐linearities ...
Wen Tan, Shuaibing Chang, Rong Zhou
openaire   +1 more source

Integration of sweet taste and metabolism determines carbohydrate reward [PDF]

, 2017
Post-ingestive signals related to nutrient metabolism are thought to be the primary drivers of reinforcement potency of energy sources. Here, in a series of neuroimaging and indirect calorimetry human studies, we examine the relative roles of caloric ...
Babbs, Richard Keith, Fobbs, Wambura, Garcia, Elizabeth, Kroemer, Nils B, Patel, Barkha, Small, Dana M, Veldhuizen, Maria Geraldine, Yeomans, Martin   +7 more
core   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Fast algorithm for calculating two-photon absorption spectra

, 1998
We report a numerical calculation of the two-photon absorption coefficient of electrons in a binding potential using the real-time real-space higher-order difference method.
A. Vaidyanathan, C. Cohen-Tannoudji, D. A. Drabold, D. Cotter, G. P. Banfi, Garnett W. Bryant, J. Li, J. Skilling, M. Murayama, M. Suzuki, O. F. Sankey, R. N. Silver, R. N. Silver, R. Tommasi, S. M. Oak, S. Nomura, S. Nomura, Shintaro Nomura, T. Iitaka, Tadashi Takemori, W. H. Press, Yoshinobu Aoyagi, Yoshiyuki Kurokawa   +22 more
core   +1 more source

PICALM::MLLT10 translocated leukemia

FEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath   +7 more
wiley   +1 more source

Single Machine connected Infinite Bus system tuning coordination control using Biogeography: Based Optimization algorithm [PDF]

FME Transactions, 2019
In this paper, the design of hybrid coordinated damping controller (power system stabilizer (PSS) and proportional integral derivative (PID) controller) is articulated as an optimization problem.
Kasilingam Gowrishankar, Pasupuleti Jagadeesh, Bharatiraja Chokkalingam, Adedayo Yusuff   +3 more
doaj  

Data Offloading in Load Coupled Networks: A Utility Maximization Framework

, 2013
We provide a general framework for the problem of data offloading in a heterogeneous wireless network, where some demand of cellular users is served by a complementary network. The complementary network is either a small-cell network that shares the same
Ho, Chin Keong, Sun, Sumei, Yuan, Di
core   +2 more sources

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source