Results 51 to 60 of about 14,727,707 (258)

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Non-linear-echo based anti-collusion mechanism for audio signals

, 2021
Non-linear-echo based anti-collusion mechanism for audio ...
Tianrui Zong (13101447), G Hua (13315455), Yong Xiang (13101027), Iynkaran Natgunanathan (13074612), W Zhou (7715300), Longxiang Gao (13081947)   +5 more
core  

Association between creatinine-to-body weight ratio and incident prediabetes in Chinese adults: a large-scale retrospective cohort study

Frontiers in Endocrinology
Background and objectiveWhile the creatinine-to-body weight ratio (Cre/BW) has emerged as a promising biomarker for muscle mass assessment, its relationship with prediabetes remains unclear.
Wushan Pan, Yuheng Liao, Yuheng Liao, Yong Han, Yong Han, Changchun Cao, Changchun Cao, Haofei Hu, Haofei Hu   +8 more
doaj   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Association between serum vitamin D and the risk of diabetic kidney disease in patients with type 2 diabetes

Frontiers in Medicine
AimsThis investigation explored the potential correlation between serum vitamin D concentration and diabetic kidney disease (DKD) among patients with type 2 diabetes mellitus (T2DM).MethodsThis cross-sectional study assessed 4,570 patients with T2DM ...
Yujie Wang, Yujie Wang, Chenggang Hu, Ying Li, Ying Li, Qi Liu, Qi Liu, Lichao Gao, Lichao Gao, Dongmei Zhang, Dongmei Zhang, Ling Cao, Ling Cao   +12 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Testing the non-linear relationship between environmental policy and economic growth in China

Frontiers in Environmental Science
IntroductionIn order to achieve the coordinated development of environmental protection and economic growth, China has implemented a series of environmental policies. However, the relationship between environmental policy and economic growth is ambiguous
Zhenhua Wang, Ning Wang, Rui Li
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source