Results 41 to 50 of about 238,753 (197)

Dendrimer Conjugates with PD‐L1‐Binding Peptides Enhance In Vivo Antitumor Immune Response

open access: yesAdvanced Healthcare Materials, EarlyView.
In this paper, a novel nanoparticle scaffold composed of dendrimers conjugated with peptide‐based immune checkpoint inhibitors, enhancing drug delivery efficacy is introduced. By conjugating PD‐L1‐binding peptides to dendrimers, multivalent binding effects are harnessed, resulting in enhanced binding affinity, prolonged half‐life, and improved ...
DaWon Kim   +11 more
wiley   +1 more source

Formalizing Determinacy of Concurrent Revisions [PDF]

open access: yesarXiv, 2019
Concurrent revisions is a concurrency control model designed to guarantee determinacy, meaning that the outcomes of programs are uniquely determined. This paper describes an Isabelle/HOL formalization of the model's operational semantics and proof of determinacy.
arxiv  

Designing for Degradation: Transient Devices Enabled by (Nano)Cellulose

open access: yesAdvanced Materials, EarlyView.
Recent progress in transient devices enabled by (nano)cellulosic materials is reviewed. Transiency mechanisms, advantages of nanocelluloses, and a suite of applications are discussed. A circular thinking approach coupled with life cycle assessment is applied to critically revisit the potential, advantages, and challenges of nanocellulose‐enabled ...
Lucas J. Andrew   +2 more
wiley   +1 more source

Treatment-control comparisons in platform trials including non-concurrent controls [PDF]

open access: yesarXiv
Shared controls in platform trials comprise concurrent and non-concurrent controls. For a given experimental arm, non-concurrent controls refer to data from patients allocated to the control arm before the arm enters the trial. The use of non-concurrent controls in the analysis is attractive because it may increase the trial's power of testing ...
arxiv  

DGCC:A New Dependency Graph based Concurrency Control Protocol for Multicore Database Systems [PDF]

open access: yesarXiv, 2015
Multicore CPUs and large memories are increasingly becoming the norm in modern computer systems. However, current database management systems (DBMSs) are generally ineffective in exploiting the parallelism of such systems. In particular, contention can lead to a dramatic fall in performance.
arxiv  

Polyphenol‐Derived Carbonaceous Frameworks with Multiscale Porosity for High‐Power Electrochemical Applications

open access: yesAdvanced Materials, EarlyView.
This review examines the fluid dynamic behavior within carbonaceous porous structures, linking structural characteristics to electrolyte transport and electrochemical performance. Specifically, it quantitatively assesses the effect of polyphenol derivatives‐harnessed multiscale pore structures on active surface utilization and electrochemical activity ...
Minjun Kim   +3 more
wiley   +1 more source

Fray: An Efficient General-Purpose Concurrency Testing Platform for the JVM [PDF]

open access: yesarXiv
Concurrency bugs are hard to discover and reproduce. Prior work has developed sophisticated algorithms to search for concurrency bugs, such as partial order sampling (POS); however, fundamental limitations with existing platforms for concurrency control hinder effective testing of real-world software.
arxiv  

The Impact of Timestamp Granularity in Optimistic Concurrency Control [PDF]

open access: yesarXiv, 2018
Optimistic concurrency control (OCC) can exploit the strengths of parallel hardware to provide excellent performance for uncontended transactions, and is popular in high-performance in-memory databases and transactional systems. But at high contention levels, OCC is susceptible to frequent aborts, leading to wasted work and degraded performance ...
arxiv  

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