Results 41 to 50 of about 14,626,183 (289)

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Shifting Baselines and the Conservation of Non‐Native Species [PDF]

Conservation Biology, 2014
Peer ...
openaire   +2 more sources

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

Non-native invasive species and novel ecosystems [PDF]

F1000Prime Reports, 2015
Invasions by non-native species have caused many extinctions and greatly modified many ecosystems and are among the major anthropogenic global changes transforming the earth. Beginning in the mid-1980s, a dramatic burst of research in invasion biology has revealed a plethora of previously unrecognized impacts and laid bare the scope of the phenomenon ...
openaire   +2 more sources

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Cabomba caroliniana Gray (Cabombaceae) invades major waterways in Belgium

Knowledge and Management of Aquatic Ecosystems, 2019
Recently, unattached viable stem fragments of the invasive macrophyte Cabomba caroliniana Gray were found at several locations in two canals in northern Belgium.
Scheers Kevin, Denys Luc, Jacobs Indra, Packet Jo, Smeekens Vincent, Adriaens Tim   +5 more
doaj   +1 more source

Non‐native flora of Italy: Species distribution and threats

Plant Biosystems - An International Journal Dealing with all Aspects of Plant Biology, 2010
Abstract In this paper, we provide an overview of the distribution and invasive status of non‐native species in the Italian flora across its administrative regions, biogeographic regions and main land use types, and a synthesis of current knowledge on the threats they pose within the country. The information on non‐native plant species collected during
CELESTI, Laura, A. Alessandrini, P. V. Arrigoni, S. Assini, E. Banfi, E. Barni, M. Bovio, G. Brundu, M. R. Cagiotti, I. Camarda, CARLI, EMANUELA, F. Conti, E. Del Guacchio, G. Domina, S. Fascetti, G. Galasso, L. Gubellini, F. Lucchese, P. Medagli, N. G. Passalacqua, S. Peccenini, L. Poldini, PRETTO, FRANCESCA, F. Prosser, M. Vidali, L. Viegi, M. C. Villani, T. Wilhalm, BLASI, Carlo   +28 more
openaire   +11 more sources

Pollination ecology of the invasive tree tobacco Nicotiana glauca: comparisons across native and non-native ranges [PDF]

, 2012
Interactions with pollinators are thought to play a significant role in determining whether plant species become invasive, and ecologically generalised species are predicted to be more likely to invade than more specialised species.
Ollerton, Jeff, Izhaki, Ido, Wilson, Ian, Shawn Connerty, Julia Lock, Leah Parker, Schueller, Sheila K., Andrea A. Cocucci, Stout, Jane C., Stout, Jane C, Cocucci, Andrea Aristides, Lock, Julia, Ian Wilson, Geerts, Sjirk, Nattero, Julieta, Jane C, Schueller, Sheila, Sheila K, Ido Izhaki, Stella Watts, Jeff Ollerton, Anton Pauw, Geerts, Sirjk, Pauw, Anton, Cocucci, Andrea A, Sjirk Geerts, Córdoba Xjjc Córdoba, Watts, Stella, Parker, Leah, Connerty, Shawn, Julieta Nattero   +30 more
core  

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Non-native Species and the Aesthetics of Nature [PDF]

, 2017
(Uploaded by Plazi for the IPBES Invasive Alien Species Assessment) How humans perceive and judge nature and relate it to their life is shaped by emotional, cognitive, cultural, and social factors. Whether a species is considered native, non-native, or invasive can affect such aesthetics of nature by interacting with our emotions, affronting or ...
Kueffer, Christoph, Kull, Christian A., Vilà, Montserrat, Hulme, Philip E.   +3 more
openaire   +3 more sources