Results 41 to 50 of about 361,927 (254)

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

Non‐native flora of Italy: Species distribution and threats

Plant Biosystems - An International Journal Dealing with all Aspects of Plant Biology, 2010
Abstract In this paper, we provide an overview of the distribution and invasive status of non‐native species in the Italian flora across its administrative regions, biogeographic regions and main land use types, and a synthesis of current knowledge on the threats they pose within the country. The information on non‐native plant species collected during
CELESTI, Laura, A. Alessandrini, P. V. Arrigoni, S. Assini, E. Banfi, E. Barni, M. Bovio, G. Brundu, M. R. Cagiotti, I. Camarda, CARLI, EMANUELA, F. Conti, E. Del Guacchio, G. Domina, S. Fascetti, G. Galasso, L. Gubellini, F. Lucchese, P. Medagli, N. G. Passalacqua, S. Peccenini, L. Poldini, PRETTO, FRANCESCA, F. Prosser, M. Vidali, L. Viegi, M. C. Villani, T. Wilhalm, BLASI, Carlo   +28 more
openaire   +10 more sources

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Cabomba caroliniana Gray (Cabombaceae) invades major waterways in Belgium

Knowledge and Management of Aquatic Ecosystems, 2019
Recently, unattached viable stem fragments of the invasive macrophyte Cabomba caroliniana Gray were found at several locations in two canals in northern Belgium.
Scheers Kevin, Denys Luc, Jacobs Indra, Packet Jo, Smeekens Vincent, Adriaens Tim   +5 more
doaj   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

Diversity and biotic homogenization of urban land-snail faunas in relation to habitat types and macroclimate in 32 central European cities.

PLoS ONE, 2013
The effects of non-native species invasions on community diversity and biotic homogenization have been described for various taxa in urban environments, but not for land snails.
Michal Horsák, Zdeňka Lososová, Tomáš Čejka, Lucie Juřičková, Milan Chytrý   +4 more
doaj   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Recovering Native Culture in a World of Non‐native Species

Conservation Biology, 2014
Fil: Souto, Cintia Paola. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Patagonia Norte. Instituto de Investigaciones En Biodiversidad y Medioambiente. Universidad Nacional del Comahue. Centro Reg.universidad Bariloche.
Speziale, Karina Lilian, Lambertucci, Sergio Agustin, Souto, Cintia Paola, Hiraldo, Fernando   +3 more
openaire   +3 more sources

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Revisiting the Potential Conservation Value of Non‐Native Species

Conservation Biology, 2012
JEAN RICARDO SIMOES VITULE,∗ CAROLINA A. FREIRE,† DIEGO P. VAZQUEZ,‡ MARTIN A. NUNEZ,§ AND DANIEL SIMBERLOFF§ ** ∗Laboratorio de Ecologia e Conservacao, Departamento de Engenharia Ambiental, Setor de Tecnologia, Universidade Federal do Parana, 81531, 980, Curitiba, Parana, Brazil †Departamento de Fisiologia, Setor de Ciencias Biologicas, Centro ...
Vitule, Jean Ricardo Simões, Freire, Carolina A., Vazquez, Diego P., Nuñez, Martin A., Simberloff, Daniel   +4 more
openaire   +3 more sources