Non-Negative Matrix Factorization with Constraints
Haifeng Liu, Zhaohui Wu
openalex +2 more sources
Glycosylation Gene Signatures as Prognostic Biomarkers in Glioblastoma
ABSTRACT Objective Glioblastoma (GBM) is an aggressive brain tumor characterized by significant heterogeneity. This study investigates the role of glycosylation‐related genes in GBM subtyping, prognosis, and response to therapy. Methods We analyzed mRNA expression data and clinical information from The Cancer Genome Atlas (TCGA) and Gene Expression ...
Tong Zhao+4 more
wiley +1 more source
Mapping the neuroanatomical heterogeneity of OCD using a framework integrating normative model and non-negative matrix factorization. [PDF]
Han S+9 more
europepmc +1 more source
ABSTRACT Objectives To investigate whether pulse pressure or mean arterial pressure mediates the relationship between age and white matter hyperintensity load and to examine the mediating effect of white matter hyperintensities on cognition. Methods Demographic information, blood pressure, current medication lists, and Montreal Cognitive Assessment ...
Jade Hannan+8 more
wiley +1 more source
Inferring cellular and molecular processes in single-cell data with non-negative matrix factorization using Python, R and GenePattern Notebook implementations of CoGAPS. [PDF]
Johnson JAI+17 more
europepmc +1 more source
Compressing POMDPs Using Locality Preserving Non-Negative Matrix Factorization
Georgios Theocharous, Sridhar Mahadevan
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Genetic Profile and Symptom Pattern Explain Variability of Deep Brain Stimulation Effect in Dystonia
ABSTRACT Objective Bilateral globus pallidus pars interna deep brain stimulation (GPi‐DBS) is a recognized and effective treatment option for drug‐resistant dystonia patients. However, the clinical GPi‐DBS outcomes vary significantly. Herein, we explored the pre‐implant factors affecting GPi‐DBS effectiveness.
Mahboubeh Ahmadipour+6 more
wiley +1 more source
Parsing altered gray matter morphology of depression using a framework integrating the normative model and non-negative matrix factorization. [PDF]
Han S+13 more
europepmc +1 more source
jNMFMA: a joint non-negative matrix factorization meta-analysis of transcriptomics data [PDF]
Hongqiang Wang+2 more
openalex +1 more source
Towards a Fairer Non-negative Matrix Factorization
Topic modeling, or more broadly, dimensionality reduction, techniques provide powerful tools for uncovering patterns in large datasets and are widely applied across various domains. We investigate how Non-negative Matrix Factorization (NMF) can introduce bias in the representation of data groups, such as those defined by demographics or protected ...
Kassab, Lara+5 more
openaire +2 more sources