Results 131 to 140 of about 57,158 (293)

In Vitro Modeling of Human Germ Cell Development Using Pluripotent Stem Cells

Stem Cell Reports, 2018
Summary: Due to differences across species, the mechanisms of cell fate decisions determined in mice cannot be readily extrapolated to humans. In this study, we developed a feeder- and xeno-free culture protocol that efficiently induced human pluripotent
Yuncheng Zhao, Shicheng Ye, Dongli Liang, Pengxiang Wang, Jing Fu, Qing Ma, Ruijiao Kong, Linghong Shi, Xueping Gong, Wei Chen, Wubin Ding, Wenjing Yang, Zijue Zhu, Huixing Chen, Xiaoxi Sun, Jun Zhu, Zheng Li, Yuan Wang   +17 more
doaj   +1 more source

Pregnancy via Testicular Sperm Extraction for Anejaculation After Neuroblastoma Surgery

IJU Case Reports, Volume 9, Issue 1, January 2026.
ABSTRACT Background Surgical treatment of a neuroblastoma, a malignant tumor of the sympathetic nervous system, may result in ejaculatory disorder. There are no reports examining ejaculation disorders after neuroblastoma surgery. Case Presentation The patient was a 31‐year‐old Japanese male who had undergone surgery for neuroblastoma of the abdomen at ...
Jurii Karibe, Teppei Takeshima, Daiji Takamoto, Takashi Kawahara, Kimito Osaka, Jun‐ichi Teranishi, Kazuhide Makiyama, Hiroji Uemura, Yasushi Yumura   +8 more
wiley   +1 more source

Reproductive outcomes, including neonatal data, following sperm injection in men with obstructive and nonobstructive azoospermia: case series and systematic review

Clinics, 2013
We compared pregnancy outcomes following intracytoplasmic sperm injection for the treatment of male infertility according to the type of azoospermia. First, we analyzed our data from 370 couples who underwent intracytoplasmic sperm injection using sperm ...
Sandro C. Esteves, Ashok Agarwal
doaj  

Deficient Expression of DGCR8 in Human Testis is Related to Spermatogenesis Dysfunction, Especially in Meiosis I

International Journal of General Medicine, 2020
Emad Babakhanzadeh,1,2,* Ali Khodadadian,1,* Majid Nazari,1 Masoud Dehghan Tezerjani,1 Seyed Mohsen Aghaei,1 Sina Ghasemifar,1 Mehdi Hosseinnia,3 Mahta Mazaheri1,4 1Department of Medical Genetics, Shahid Sadoughi University of Medical Sciences, Yazd ...
Babakhanzadeh E, Khodadadian A, Nazari M, Dehghan Tezerjani M, Aghaei SM, Ghasemifar S, Hosseinnia M, Mazaheri M   +7 more
doaj  

Development, Live Birth and Fertility in Mouse Oocytes Penetrated by Spermatids Exposed to the HDAC Inhibitor Scriptaid

Reproductive Medicine and Biology, Volume 25, Issue 1, January/December 2026.
ABSTRACT Purpose In mouse embryos derived from round spermatid injection (ROSI), low developmental potential due to abnormal histone modification is improved by histone deacetylase (HDAC) inhibitors. However, some studies suggest that the use of such inhibitors leads to the birth of hypomorphic offspring.
Seiji Watanabe, Youichi Takemoto, Rei Inoue, Izumi Tanaka, Hironori Miyata, Yuya Makino, Motoi Nagayoshi, Daisuke Nakajima, Shigeki Fujimoto, Atsushi Tanaka   +9 more
wiley   +1 more source

Reinke’s crystals in perivascular and peritubular Leydig cells of men with nonobstructive and obstructive azoospermia: a retrospective case-control study [PDF]

, 2019
Aim To analyze the differences in the population of perivascular and peritubular Leydig cells (LC) and the number of Reinke’s crystals (RCs) in the testicles of infertile men with non-obstructive and obstructive azoospermia.
Monica Di Luca
core   +2 more sources

The frequency of follicle stimulating hormone receptor gene polymorphisms in Iranian infertile men with azoospermia

Iranian Journal of Reproductive Medicine, 2015
Background: Azoospermia is the medical condition of a man not having any measurable level of sperm in his semen. Follicle stimulating hormone (FSH) is a member of the glycoprotein hormone family that plays an important role in human reproduction because ...
Behrouz Gharesi-Fard, Zahra Ghasemi, Saeed Shakeri, Shabnam Behdin, Fatemeh Aghaei, Zahra Malek-Hosseini   +5 more
doaj  

Isolated follicle stimulated hormone deficiency in male: case report

BMC Research Notes, 2018
Background Recent rapid advances in assisted reproductive health technologies enables couples with subfertility to conceive through various intervention. Majority of treatment modalities target the female partner.
Gowri M. Ratnayake, P. N. Weerathunga, L. P. Ruwanpura, Amila Wickramasinghe, Prasad Katulanda   +4 more
doaj   +1 more source

Varicocele and non-obstructive azoospermia – where to start?

Andrology and Genital Surgery, 2017
Background. Male etiology is responsible for nearly half of cases of infertility. Frequency of azoospermia in infertile men reaches 30 %; varicocele is diagnosed in almost 40 % of the patients. Varicocele- associated infertility has traditionally been considered an indication  for surgical treatment.
A. Yu. Popova, S. I. Gamidov, R. I. Ovchinnikov, N. P. Naumov, N. G. Gasanov   +4 more
openaire   +3 more sources

A Case of Cystic Fibrosis in a Japanese Man With Congenital Bilateral Absence of the Vas Deferens and Recurrent Pancreatitis Caused by a Homozygous c.1210‐11 T > G Variant of the Cystic Fibrosis Transmembrane Conductance Regulator Gene

Reproductive Medicine and Biology, Volume 25, Issue 1, January/December 2026.
ABSTRACT Case We herein report a rare case of a Japanese man diagnosed with cystic fibrosis (CF) following a workup for male infertility and recurrent pancreatitis and discuss the clinical and diagnostic implications in a population wherein CF is exceptionally rare. A 27‐year‐old Japanese man who presented with azoospermia underwent clinical evaluation,
Tomoki Saito, Shinnosuke Kuroda, Teppei Takeshima, Takashi Kawahara, Junichi Teranishi, Jurii Karibe, Fuka Anzai, Miki Tanoshima, Kazuhide Makiyama, Yasushi Yumura   +9 more
wiley   +1 more source