Results 231 to 240 of about 985,928 (292)

A Depolarizing Leak in Sodium Bicarbonate Cotransporter NBCe1 Causes Brain Edema

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives SLC4A4 encodes electrogenic sodium bicarbonate cotransporter NBCe1, prominently expressed in kidney and brain. Recessive loss‐of‐function variants in SLC4A4 cause proximal renal tubular acidosis, no brain edema. In the brain, NBCe1 is expressed by astrocytes, where it regulates pH and mediates astrocyte volume changes.
Quinty Bisseling, Mark D. Parker, Sven Kerst, Richard A. Pasternack, Jacob Tondreau, Marjolein Breur, Gemma M. van Rooijen‐van Leeuwen, Davide Tonduti, Ettore Salsano, Alejandra Darling, Joanna A. E. van Wijk, Susanna Törnroth‐Horsefield, Marianna Bugiani, Petra J. W. Pouwels, Quinten Waisfisz, Marjo S. van der Knaap, Rogier Min   +16 more
wiley   +1 more source

Non-parametric quantile regression-based modelling of additive effects to solar irradiation in Southern Africa. [PDF]

Sci Rep
Masache A, Maposa D, Mdlongwa P, Sigauke C.   +3 more
europepmc   +1 more source

Multiple Sclerosis Relapse Activity After Ozanimod Discontinuation in DAYBREAK Trial Participants

Annals of Clinical and Translational Neurology, EarlyView.
Multiple Sclerosis Relapse Activity After Ozanimod Discontinuation in DAYBREAK Trial Participants. ABSTRACT Objective Return of disease activity is expected when patients discontinue disease‐modifying therapy (DMT) for multiple sclerosis (MS). Some MS DMTs are associated with higher‐than‐expected disease activity (rebound) after discontinuation.
Ralf Gold, Krzysztof W. Selmaj, Regina Berkovich, Jeffrey A. Cohen, Giancarlo Comi, Eva K. Havrdová, James K. Sheffield, Hetal Desai, Chun‐Yen Cheng, Jon V. Riolo, Andrew Thorpe, Erik DeBoer, Bruce A. C. Cree   +12 more
wiley   +1 more source

Non-parametric Regression Among Factor Scores: Motivation and Diagnostics for Nonlinear Structural Equation Models. [PDF]

Psychometrika
Grønneberg S, Irmer JP.
europepmc   +1 more source

Elevated Connectivity During Language Processing Is Associated With Cognitive Performance in SeLECTS

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Self‐Limited Epilepsy with Centrotemporal Spikes (SeLECTS) is associated with language impairments despite seizures originating in the motor cortex, suggesting aberrant cross‐network interactions. Here we tested whether functional connectivity in SeLECTS during language tasks predicts language performance.
Wendy Qi, Katharine Lee, Kerry C. Nix, Miguel Menchaca, Xiwei Shé, Lorelei Santa Maria, Wei Wu, Zihuai He, Fiona M. Baumer   +8 more
wiley   +1 more source

Construction and optimization of non-parametric analysis model for meter coefficients via back propagation neural network. [PDF]

Sci Rep
Yang Y, Hu R, Wang W, Zhang T.
europepmc   +1 more source

IV Thrombolysis Facilitates Interventional Reperfusion in Non‐Cardioembolic but Not Cardioembolic Stroke

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Intravenous thrombolysis (IVT) before thrombectomy for ischemic stroke may alter clot structure and procedural performance. We investigated how IVT relates to thrombectomy metrics across stroke etiologies. Methods We performed a time‐to‐event analysis of consecutive patients with anterior circulation large vessel occlusion (acLVO ...
Annahita Sedghi, Daniel P. O. Kaiser, Martin Arndt, Norma J. Diel, Erik Simon, Witold H. Polanski, Volker Puetz, Hagen B. Huttner, Timo Siepmann   +8 more
wiley   +1 more source

Development of a quantitative prediction algorithm for human cord blood-derived CD34⁺ hematopoietic stem-progenitor cells using parametric and non-parametric machine learning models. [PDF]

Sci Rep
Leung CK, Zhu P, Loke I, Tang KF, Leung HC, Yeung CF.   +5 more
europepmc   +1 more source

Trend analysis of reaction parameters and properties of plant-mediated green synthesized selenium nanoparticles using non-parametric statistical methods (Mann-Kendall trend test, Sen's slope estimator, ANOVA) and their applications in the modern world: a critical perspective. [PDF]

RSC Adv
Islam MS, Sams SU, Malitha SB, Alam MZ.
europepmc   +1 more source

A novel non-parametric statistical method in reliability theory: Mathematical characterization and analysis of asymmetric data in the fields of biological sciences and engineering. [PDF]

Heliyon
Al-Essa LA, Etman WBH, Eliwa MS, El-Morshedy M, El-Sagheer RM.   +4 more
europepmc   +1 more source