Smaller is better: nanobodies meet NMR
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley +1 more source
Parametric vs. non-parametric methods for estimating option implied risk-neutral densities: the case of the exchange rate Mexican peso – US dollar. [PDF]
This research paper presents statistical comparisons between two methods that are commonly used to estimate option implied Risk-Neutral Densities (RND). These are: 1) mixture of lognormals (MXL); and, 2) volatility function technique (VFT). The former is
Israel Felipe Mora Cuevas +1 more
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Investigating the Impacts of Climate and Land Use Change on the Hydrologic Characteristics in the Sub-Basins of the Dez River, Middle East [PDF]
Human activities and the climate change affects the river flow therefore monitoring flow rate of river for an extended period can reveal the detail of involved mechanisms in these changes.
Zohreh Khorsandi Kouhanestani
doaj +1 more source
A Non-Parametric Bayesian Method for Inferring Hidden Causes
We present a non-parametric Bayesian approach to structure learning with hidden causes. Previous Bayesian treatments of this problem define a prior over the number of hidden causes and use algorithms such as reversible jump Markov chain Monte Carlo to move between solutions. In contrast, we assume that the number of hidden causes is unbounded, but only
Wood, F, Griffiths, T, Ghahramani, Z
openaire +5 more sources
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley +1 more source
An innovative approach based on real-world big data mining for calculating the sample size of the reference interval established using transformed parametric and non-parametric methods. [PDF]
Ma C +8 more
europepmc +1 more source
Financial distress in the hotel industry: Evidence from a multidimensional performance framework
Purpose – This study examines the multidimensional determinants of financial distress in joint-stock hotel companies using the KRAS framework, comprising the continuity, reputation, activity, and structure dimensions.
Miroslav Čavlin +2 more
doaj +1 more source
Functional magnetic resonance imaging (fMRI) is a popular method to probe the functional organization of the brain using hemodynamic responses. In this method, volume images of the entire brain are obtained with a very good spatial resolution and low ...
Sheyda Bahrami, Mousa Shamsi
doaj +1 more source
Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana +3 more
wiley +1 more source
Non-parametric production analysis under alternative price conditions. [PDF]
The literature on non-parametric production analysis has formulated tests for profit maximizing behavior that do not require a parametric specification of technology.
Kuosmanen, T, Cherchye, Laurens, Post, T
core

