Results 131 to 140 of about 16,220,352 (310)

GDP nowcasting with ragged-edge data: a semi-parametric modeling [PDF]

open access: yes
This paper formalizes the process of forecasting unbalanced monthly datasets in order to obtain robust nowcasts and forecasts of quarterly gross domestic product (GDP) growth rate through a semi-parametric modeling.
Patrick Rakotomarolahy   +2 more
core  

Expect the unexpected: Augmented mixture models for black-hole-population studies

open access: yesAstronomy & Astrophysics
Context. Black-hole-population studies are currently performed either using astrophysically motivated models (informed but rigid in their functional forms) or via non-parametric methods (flexible, but not directly interpretable). Aims.
Rinaldi Stefano
doaj   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers

open access: yesFEBS Letters, EarlyView.
Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui   +4 more
wiley   +1 more source

Efficiency Analysis of German Electricity Distribution Utilities : Non-Parametric and Parametric Tests [PDF]

open access: yes
This paper applies parametric and non-parametric and parametric tests to assess the efficiency of electricity distribution companies in Germany. We address traditional issues in electricity sector benchmarking, such as the role of scale effects and ...
von Hirschhausen, Christian R.   +1 more
core  

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

[19] J. D. Gibson and M. L. Melsa, Introduction to Non-Parametric Detection

open access: yes, 2008
[16] H. V. Poor and M. Tanda, “Multiuser detection in impulsive channels,” Ann. Telecommun., vol. 54, pp. 392–400, Jul./Aug. 1999. [17] P. J. Huber, Robust Statistics. New York: Wiley, 1981. [18] B. Seyfe and A. R.
New York   +7 more
core  

Graduating the age-specific fertility pattern using Support Vector Machines

open access: yesDemographic Research, 2009
A topic of interest in demographic literature is the graduation of the age-specific fertility pattern. A standard graduation technique extensively used by demographers is to fit parametric models that accurately reproduce it.
Anastasia Kostaki   +3 more
doaj  

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

COOPER-framework: A Unified Standard Process for Non-parametric Projects [PDF]

open access: yes
Practitioners assess performance of entities in increasingly large and complicated datasets. If non-parametric models, such as Data Envelopment Analysis, were ever considered as simple push-button technologies, this is impossible when many variables are ...
De Witte, K., Emrouznejad, A.
core  

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