Results 61 to 70 of about 4,109,960 (295)

Universal Sample Size Invariant Measures for Uncertainty Quantification in Density Estimation

Entropy, 2019
Previously, we developed a high throughput non-parametric maximum entropy method (PLOS ONE, 13(5): e0196937, 2018) that employs a log-likelihood scoring function to characterize uncertainty in trial probability density estimates through a scaled quantile
Jenny Farmer, Zach Merino, Alexander Gray, Donald Jacobs   +3 more
doaj   +1 more source

Overlapping Observations in Credit Risk Models

Econometric Research in Finance, 2023
Parameters in logistic regression models for probability of default are typically estimated using the maximum likelihood method. The aim of this paper is to verify whether the use of overlapping observations improves precision or causes deterioration of
Dobromił Serwa
doaj   +1 more source

Methods for sampling and inference with non-probability samples

, 2021
Non-probability samples are a topic of growing relevance in academic and applied research as well as national statistical institutes. This deliverable discusses the major statistical challenges that arise when using non-probability samples, as well as methodological advances for improving the reliability of results and conclusions that are obtained ...
Lenau, Simon, Marchetti, S., Münnich, Ralf, Pratesi, Monica, Salvati, N., Shlomo, N., Schirripa Spagnolo, F., Zhang, L.-C.   +7 more
openaire   +1 more source

PICALM::MLLT10 translocated leukemia

FEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath   +7 more
wiley   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source

The Effect of Hospice on End-of-Life Costs for Terminal Medicare Patients With HIV

Inquiry: The Journal of Health Care Organization, Provision, and Financing, 2020
One-quarter of annual Medicare expenses in the traditional program (non-Medicare Advantage) are expended for 5% of Medicare enrollees, with much of this expenditure occurring in the last year of life. Hospice use may reduce end-of-life costs.
Arleen A. Leibowitz PhD, Diane Tan MSPH, Jennifer L. Gildner MS   +2 more
doaj   +1 more source

Image-guided superficial radiation therapy has superior 2-year recurrence probability to Mohs micrographic surgery

Clinical and Translational Radiation Oncology, 2023
Introduction: Non-melanoma skin cancers (NMSCs) are the most common cancers in the USA, and their incidence is rising. Mohs micrographic surgery (MMS) is commonly performed to excise NMSCs.
Erin M. McClure, Geoffrey Sedor, Yuxuan Jin, Michael W. Kattan   +3 more
doaj   +1 more source

Pretest estimation in combining probability and non-probability samples

Electronic Journal of Statistics, 2023
Multiple heterogeneous data sources are becoming increasingly available for statistical analyses in the era of big data. As an important example in finite-population inference, we develop a unified framework of the test-and-pool approach to general parameter estimation by combining gold-standard probability and non-probability samples.
Gao, Chenyin, Yang, Shu
openaire   +3 more sources

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

A novel framework for debris flow susceptibility assessment considering the uncertainty of sample selection

Geomatics, Natural Hazards & Risk
The uncertainty arising from random sampling of non-debris flow samples significantly impacts the accuracy of debris flow susceptibility assessments (DFSA).
Can Yang, Jiao Wang, Guotao Zhang
doaj   +1 more source