Results 121 to 130 of about 487,224 (310)

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

Classifying non-profit organisations in China

, 2019
Classification is the foundation of legislation. The history of non-profit classification in China is short and the criteria are very unstable. Since the first laws were issued in the early 20th century, there has been only one general term for non-profit organizations (NPOs), which is “association”.
openaire   +1 more source

Some comparative economics of the organization of sports: competition and regulation in north American vs. European professional team sports leagues [PDF]

This article contends that a new research avenue is open to comparative economics which is the economic comparison between American (closed) and European (open) professional team sports leagues.
Wladimir Andreff
core  

Unlocking the potential of creative commons for Hong Kong's education and creative sectors [PDF]

, 2010
Creative Commons is a non-profit organisation founded by Professor Lawrence Lessig in the United States. The organisation seeks to replace the default rule of "All Rights Reserved" under copyright law with a fl exible "Some Rights Reserved" approach in ...
Kwok, KHF
core  

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

Forms of Employment and Green Project Management in Non-profit Organisations

Zeszyty Naukowe Uniwersytetu Ekonomicznego w Krakowie
Objective: The paper discusses the topic of non-profit organisations (NPO) with a particular emphasis on the relationship between Green (Sustainable) Project Management (GPM) and the forms of employment.
Anna Zabłocka-Kluczka, Anna Marciszewska, Renata Brajer-Marczak   +2 more
doaj   +1 more source

Electronic purchasing: determining the optimal roll-out strategy [PDF]

, 2002
Electronic purchasing (EP), also known as electronic ordering through catalogs is the most established form of e-procurement nowadays, yet still in its infancy.
Heijboer, Govert, Telgen, Jan
core   +1 more source

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

Molecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck, Nele De Meulenaere, Thomas Vanpoucke, Joe Ibrahim, Dieter Peeters, Suresh Krishan Yogeswaran, Wen Wen, Paul Van Schil, Jeroen M. H. Hendriks, Jo Raskin, Jan van Meerbeeck, Guy Van Camp, Ken Op de Beeck   +12 more
wiley   +1 more source

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

Molecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié, Umberto Malapelle, Catherine Alix‐Panabières, Claus Lindbjerg Andersen, Sandra Chlebowski, Vivien Lake, Caroline Lacoux, Virginie Lespinet‐Fabre, Olivier Bordone, Simon Heeke, Christophe Bontoux, Ellen Heitzer, Klaus Pantel, Paul Hofman   +13 more
wiley   +1 more source

Communicating 'dual citizenship' - how do charities manage their reputation for 'good works' while undertaking commercial activities [PDF]

, 2009
Charities and not-for-profit organisations have traditionally eschewed commercial operations in favour of direct fund-raising from supporters. Building on Goodall’s (2000) exploration of sectoral values, it can be said that competitive pressures are ...
Watson, Tom, White, Anna Marie
core