Results 131 to 140 of about 487,224 (310)
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Hybridity in Non-profit Sport Organisations: Organisational Challenges
, 2019 This study examines the concept of organisational hybridity and its applicability in non-profit sport organisations (NPSOs). In the non-profit sector, hybridity refers to “the complex organizational forms that arise as voluntary, charitable, and community organizations confront differentiated task, legitimacy, or resource environments” (Skelcher ...
Zeimers, Géraldine +4 more
openaire +1 more source
Building Bridges Between the Poor and the Banking System: A Study of Sanghamithra Rural Financial Services [PDF]
The paper is about Sanghamithra Rural Financial Services. It traces the growth of Sanghamithra from the time it was conceived till its completion of the fourth year of operations.
Sriram M S
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Business activities to use during the low season [PDF]
, 2018 The objective of this work is to find alternative activities or businesses that contrast the low winter season of an organisation. The research methods are mixed, using a quantitative method with a survey of 50 people and a qualitative method with ...
Basurto, Juan, Yaeghoobi, Ehsan
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Next‐generation proteomics improves lung cancer risk prediction
Molecular Oncology, EarlyView.This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj +4 more
wiley +1 more source
Developing indicators to measure Technology Institutes` performance. [PDF]
Technology institutes (TIs) are non-profit innovation and technology organisations aimed to encourage competitiveness of firms. They are a key organisation in the Spanish National Innovation System because of their size and closeness to the productive ...
Barge, A., Modrego, Aurelia, Núñez, R.
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Evaluating whether a change in organisational structure would improve its competitive advantage [PDF]
, 2017 The purpose of this research is to study and analyse the internal and external structure of Ultimate Clean ltd, where I do work. We have put concentration on background of the company in the starting.
Kaur, Sarbjeet, Mather, Geoffrey
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Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
Molecular Oncology, EarlyView.WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
Managing reputation for ‘good works’ while undertaking commercial activities: Communication best practice guidelines for charities [PDF]
, 2010 Charities and not-for-profit organisations have traditionally eschewed commercial operations in favour of direct fund-raising from supporters. Competitive pressures, however, are driving charities to take on ‘dual citizenship’ through activity in both ...
Watson, Tom, White, Anna Marie
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