Results 151 to 160 of about 1,607,573 (385)

Increased national critical care demands were associated with a higher mortality of intubated COVID-19 patients in Japan: a retrospective observational study

open access: yesJournal of Intensive Care
Background There was no study to investigate the association between the national surge of Coronavirus disease 2019 (COVID-19) patients and the mortality of mechanically ventilated COVID-19 patients.
Kazuya Kikutani   +10 more
doaj   +1 more source

The Jurisprudence of Interests translated and edited by M. Magdalena Schoch [PDF]

open access: yes, 1948
The  purpose  of  this  report  is  to  examine  and  describe  how  an  elite  sports organization uses  implementation  of  values  to  strengthen  the  organizational culture and the strategy.
Sayre, Paul
core   +1 more source

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

open access: yesFEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li   +8 more
wiley   +1 more source

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

open access: yesFEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth   +6 more
wiley   +1 more source

Passion with Purpose A Case Study of St. Jude Children’s Research Hospital [PDF]

open access: yes, 2018
St. Jude Children’s Research Hospital is “leading the way the world understands, treats, and defeats childhood cancer and other life threatening diseases” (St. Jude Children’s Research Hospital). Fifty-five years ago when St.
Favuzza, Allyson
core   +1 more source

Combined 5‐aminolevulinic acid and ferric ammonium citrate treatment promotes hair follicle growth by activating dermal papilla cells

open access: yesFEBS Open Bio, EarlyView.
5‐Aminolevulinic acid combined with ferric ammonium citrate (5‐ALA/FAC) stimulates dermal papilla cell activity and promotes hair follicle growth. The treatment enhances ERK and AKT signaling, increases hair‐inductive gene expression, and restores dermal papilla function suppressed by dihydrotestosterone and oxidative stress, resulting in enhanced hair
Han‐Wook Ryu, Eok‐Soo Oh, Sewoon Kim
wiley   +1 more source

The role of an anesthesiologist in the organization and provision of specialized palliative care for children

open access: yesZdorovʹe Rebenka
Background. In this article, we examined the role of a pediatric anesthesiologist in the organization and provision of palliative care for children and their families, which is within his competence.
В.І. Снісарь   +4 more
doaj   +1 more source

The Shepherd’s Center of Richmond: Opportunities for Meaning and Personal Growth through Service [PDF]

open access: yes, 2006
Educational Objectives 1. To inform Virginians about The Shepherd’s Center of Richmond, a non-profit service organization by, with, and for older adults. 2.
Frank, Linda
core   +1 more source

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