Results 181 to 190 of about 57,469 (257)

Contribution of donor hospital characteristics to deceased donor organ recovery rates. [PDF]

Am J Transplant
Lopez R, Mohan S, Vail EA, Rodrigue JR, Arrigain S, Brosi D, LaVanchy R, Nydam T, Schold JD.   +8 more
europepmc   +1 more source

Re‐Purposing Sapropterin (Kuvan) for ACTA2‐Related Multisystemic Smooth Muscle Dysfunction Syndrome: A Translational Mechanistic and First‐In‐Human Therapeutic Report

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Multisystemic smooth muscle dysfunction syndrome (MSMDS) is an ultra‐rare, ACTA2‐related disorder characterized by severe cerebrovascular disease, aortic aneurysms, and smooth muscle dysfunction. Using molecular dynamics simulations and in silico drug screening, we identified that sapropterin dihydrochloride (Kuvan) is a candidate capable of ...
Moran Hausman‐Kedem, Noa Bielopolski, Vijai Krishnan, Shane Wald‐Altman, Shelly I Shrian, Omer Bar‐Yosef, Livia Kapusta, Claire Shamber, Patricia L. Musolino, Miguel Weil   +9 more
wiley   +1 more source

The Price of Precision: A Critical Review of Molecular Diagnostics in Glioma, From Guidelines to Global Disparities

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Gliomas have undergone a profound redefinition over the past decade, transitioning from morphology‐based entities to biologically coherent diseases defined by molecular alterations. The 2021 WHO Classification of Tumors of the Central Nervous System and its 2022 update formalize this shift, establishing integrated diagnosis as the global ...
Maria Guarnaccia, Sebastiano Cavallaro
wiley   +1 more source

Quality and reliability of weight management short videos on TikTok and Bilibili: cross-sectional study. [PDF]

Sci Rep
Han L, Liu F, Wang Z, Tang N, Li X, Liu X, Wang Y, Liu H.   +7 more
europepmc   +1 more source

Insights into healthcare public managers' compensation: Influential factors and sustainable financing solutions: A scoping review. [PDF]

J Educ Health Promot
Alayi R, Nikoomanesh M, Nejhad SMM, Zali ME.   +3 more
europepmc   +1 more source

Formal and Informal Social Care in People With Rheumatic and Musculoskeletal Diseases: A Cross‐Sectional Multicenter Survey

Arthritis Care &Research, EarlyView.
Objective Rheumatic and musculoskeletal diseases (RMDs) are leading causes of physical disability, necessitating support with activities of daily living. This study describes social care received by patients with RMDs in two disparate regions of England: Salford (urban) and Norfolk (rural).
Mehreen Somro, Karen Durrant, William G. Dixon, John McBeth, Alex MacGregor, Max Yates, Jenny H. Humphreys   +6 more
wiley   +1 more source

Unionization, Ownership Status, and Direct Care Worker Turnover.

JAMA Netw Open
Gusoff GM, Jang H, Spertus D, Abraham-Aggarwal K, Avgar A, Sterling M.   +5 more
europepmc   +1 more source

A study on the mechanism of how network relationship strength affects the work development of college sports associations. [PDF]

Front Psychol
Zhu S, She A.
europepmc   +1 more source

Clinical Significance of Therapeutic Drug Level Monitoring for Mycophenolate in Patients With Extrarenal Systemic Lupus Erythematosus—A Systematic Review and Meta‐Analysis

Arthritis Care &Research, EarlyView.
Objective Clinical response to mycophenolic acid (MPA) is highly heterogeneous; thus, therapeutic drug level monitoring (TDM) may help improve treatment efficacy. This systematic review and meta‐analysis examined therapeutic ranges for MPA levels associated with better outcomes and safety in patients with systemic lupus erythematosus (SLE ...
Zahraa Qamhieh, Dalia Sriwi, Callie Saric, Tripti Singh, Christie M. Bartels, Shivani Garg   +5 more
wiley   +1 more source

Editorial: Repurposing for small population needs. [PDF]

Front Med (Lausanne)
Giannuzzi V, Fetro C, Ollivier C, Della Pasqua O.   +3 more
europepmc   +1 more source