Results 191 to 200 of about 12,220,401 (374)

Long non-coding RNA SNHG16 promotes human placenta-derived mesenchymal stem cell proliferation capacity through the PI3K/AKT pathway under hypoxia

, 2022
Xudong Feng, Jiahang Zhou, Jun-Yao Chen, Bing Feng, Ruitian Hu, Jian Wu, Qiaoling Pan, Jinfeng Yang, Jiong Yu, Hongcui Cao   +9 more
openalex   +1 more source

Redox regulation meets metabolism: targeting PRDX2 to prevent hepatocellular carcinoma

Molecular Oncology, EarlyView.
PRDX2 acts as a central redox hub linking metabolic dysfunction‐associated steatohepatitis (MASH) to hepatocellular carcinoma (HCC). In normal hepatocytes, PRDX2 maintains redox balance and metabolic homeostasis under oxidative stress. In contrast, during malignant transformation, PRDX2 promotes oncogenic signaling, stemness, and tumor initiation ...
Naroa Goikoetxea‐Usandizaga, María Luz Martinez‐Chantar, Carolina Conter   +2 more
wiley   +1 more source

Erratum: Promotion of non-small cell lung cancer tumor growth by <i>FHL2</i> via inducing angiogenesis and vascular permeability. [PDF]

J Thorac Dis
Editorial Office.
europepmc   +1 more source

Long non‑coding RNA ENST00000547547 inhibits cell proliferation, invasion and migration in colorectal cancer cells

, 2018
Xiaohui Ai, Qingliang Lei, Xiaoping Shen, Jian Li, Chaoqun Cen, Gang Xie, Bo Luo, Wenshuo Zhu, Gui Hu, Hao Wu, Miao Chen, Xiaorong Li, Changwei Lin   +12 more
openalex   +2 more sources

NUCLEAR NON-PROLIFERATION AND EXPORT CONTROL [PDF]

, 2002
Korosawa, Mitsuru
core  

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

The impact of three amino acids with distinct electrical properties on the synthesis of α-casein by MAC-T cells. [PDF]

Sci Rep
Ding Y, Xie L, Yang M, Zhang X, Yang L, Ren W, Luo R, Yang Y, Zhang H, Shao W.   +9 more
europepmc   +1 more source

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

Molecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli, Alessio Bevilacqua, Mathias Wenes, Denis Migliorini, Lars van der Veen, Sigrid S Skånland, Giusy Di Conza, Kjetil Taskén   +7 more
wiley   +1 more source

Maternal Embryonic Leucine Zipper Kinase (<i>MELK</i>) in Cancer: Biological Functions, Therapeutic Potential, and Controversies. [PDF]

Biology (Basel)
Alzeer AM, Al-Lahham S.
europepmc   +1 more source

The Mechanism of Long Non-Coding RNA SNHG7 in Cholangiocarcinoma Cell Proliferation, Migration, and Epithelial-Mesenchymal Transition

, 2022
Jisen Zhao, Yang Yu, Yuanlong Zhou, Yuan Wang, Sheng Chen, Shujie Cheng   +5 more
openalex   +2 more sources