Results 111 to 120 of about 29,450 (234)

Sodium–glucose cotransporter 2 inhibition and injection burden in mild diabetic macular edema: An exploratory post hoc analysis of the COMET trial

Journal of Diabetes Investigation, EarlyView.
Combining oral sodium‐glucose cotransporter 2 inhibitors with reduced intravitreal injections of anti‐vascular endothelial growth factor showed potential efficacy for mild diabetic macular edema. ABSTRACT Aims To investigate the potential of sodium–glucose cotransporter 2 inhibitors (SGLT2i) as a less invasive treatment option for mild diabetic macular
Yoko Takatsuna, Ryoichi Ishibashi, Masaya Koshizaka, Tomoaki Tatsumi, Takayuki Baba, Shuichi Yamamoto, Koutaro Yokote   +6 more
wiley   +1 more source

The positive correlation between the progressive photoreceptor damage and the increased macular leakage indicating the severity of diabetic retinopathy

Journal of Diabetes Investigation, EarlyView.
The dark area of photoreceptor cells, as measured by adaptive optics laser scanning ophthalmoscopy, shows significant enlargement with the progression of diabetic retinopathy (DR). A similar trend is observed for macular vascular leakage assessed by fundus fluorescein angiography. A positive correlation exists between these two parameters, suggesting a
Qi Fang, Bingjie Qiu, Xinyue Xu, Wei Jia, Ru Wang, Qianfeng Wang, Wei Qiang, Lei Zhang, Jingfa Zhang, Haiyan Wang   +9 more
wiley   +1 more source

Simulation of long-term impact of intravitreal anti-VEGF therapy on patients with severe non-proliferative diabetic retinopathy. [PDF]

BMJ Open Ophthalmol, 2023
Nguyen QD, Moshfeghi AA, Lim JI, Ponomareva E, Chauhan A, Rao R, Sherman S.   +6 more
europepmc   +1 more source

Intestinal epithelial injury and inflammation after physical work in temperate and hot environments in older men with hypertension or type 2 diabetes

Experimental Physiology, EarlyView.
Abstract We tested whether older adults with well‐controlled type 2 diabetes or hypertension, compared with age‐matched adults without chronic disease, exhibit greater intestinal damage, microbial translocation and inflammation during exertional heat stress.
Ben J. Lee, Tessa R. Flood, Sophie L. Russell, James J. McCormick, Kelli E. King, Naoto Fujii, Tatsuro Amano, Sean Notley, Glen P. Kenny   +8 more
wiley   +1 more source

Fenofibrate for the prevention of progression of non-proliferative diabetic retinopathy: review, consensus recommendations and guidance for clinical practice. [PDF]

Int J Ophthalmol, 2022
Ngah NF, Muhamad NA, Abdul Aziz RA, Mohamed SO, Ahmad Tarmizi NA, Adnan A, Asnir ZZ, Hussein Z, Siew HF, Mohamed M, Lodz NA, Valayatham V.   +11 more
europepmc   +1 more source

Treatment of the Early Stages of Diabetic Retinopathy

Diabetes is considered an epidemic of the 21st century, and the most common microvascular complication, which affects every third patient, is diabetic retinopathy.
Jerzy Mackiewicz
core   +1 more source

Effect of foot immersion and neck cooling on renal, intestinal, immune and inflammatory markers in older adults exposed to extreme heat

Experimental Physiology, EarlyView.
Abstract Older adults with reduced thermoregulatory capabilities are increasingly at risk of heat‐related pathophysiological outcomes (e.g., acute kidney injury, heatstroke) due to increasingly frequent, prolonged and intense heatwaves. Foot immersion and neck cooling have been proposed as practical, non‐electrical cooling strategies for protecting ...
Thomas McCarthy, Ben J. Lee, James J. McCormick, Kelli E. King, Emma R. McCourt, Luana C. Main, Robert D. Meade, Glen P. Kenny   +7 more
wiley   +1 more source

Intraretinal Microvascular Abnormalities and Venous Beading Have Different Genetic Profiles in Caucasian Patients with Non-Proliferative Diabetic Retinopathy. [PDF]

Vision (Basel), 2023
Pearce E, Sivaprasad S, Broadgate S, Kiire C, Downes SM, Halford S, Chong V.   +6 more
europepmc   +1 more source

Therapeutic potential of okra (Abelmoschus esculentus) in dysglycaemia and metabolic dysfunction: A systematic review and meta‐analysis across the diabetes spectrum

Experimental Physiology, EarlyView.
Abstract The aim of this systematic review and meta‐analysis was to evaluate comprehensively the therapeutic potential of Abelmoschus esculentus (okra) supplementation across the diabetes spectrum of key metabolic risk factors. A search was conducted in PubMed, Scopus, Web of Science, EMBASE and the Cochrane Library, up to 23 July 2025, to identify ...
Ali Jafari, Helia Mardani, Mohammad Amin Karimi, MohammadHossein Sahami Gilan, Helia Hemmat, Fatemeh Shoja, Nooshin Enayati Soofi, Ghazaleh Eslamian   +7 more
wiley   +1 more source

Pseudophakic Cystoid Macular Oedema (PCME) Prevention in Patients with Non-Proliferative Diabetic Retinopathy (NPDR)-Randomized Controlled Trial. [PDF]

Medicina (Kaunas), 2022
Jukić A, Kasalica Žužul R, Pavan J, Lovrić M, Kozmar A, Plavec D, Kuzman T, Kalauz M, Jukić T.   +8 more
europepmc   +1 more source