Novel optical coherence tomography angiography biomarkers in the diagnosis and assessment of diabetic macular edema and diabetic macular ischemia in patients with non-proliferative diabetic retinopathy. [PDF]
Thaker S, Kumar V, Singh U, Kumar S.
europepmc +1 more source
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Effect of calcium dobesilate on intraretinal cysts and exudates in non-proliferative diabetic retinopathy: a Fiji ImageJ analysis. [PDF]
Kutluksaman B, Dal A, Çıtırık M.
europepmc +1 more source
Dapagliflozin prevents methylglyoxal‐induced retinal cell death in ARPE‐19 cells
Diabetic macular oedema is a diabetes complication of the eye, which may lead to permanent blindness. ARPE‐19 are human retinal cells used to study retinal diseases and potential therapeutics. Methylglyoxal is a compound increased in uncontrolled diabetes due to elevated blood glucose.
Naina Trivedi +7 more
wiley +1 more source
Remote Ischemic Conditioning for Non-Proliferative Diabetic Retinopathy (RIC-NPDR): study protocol for a randomized controlled trial. [PDF]
Wang XZ, He S, Li Z, Ren CH, Zhang XX.
europepmc +1 more source
Reduced Vessel Density in the Mid-Periphery and Peripapillary Area of the Superficial Capillary Plexus in Non-Proliferative Diabetic Retinopathy. [PDF]
Chaher A +3 more
europepmc +1 more source
A multi‐stage transfer learning framework systematically optimizes CNN architectures for diabetic retinopathy detection and risk stratification from fundus images. EfficientNetB7 achieves 96% accuracy while a survival‐inspired model generates continuous risk scores aligned with DR severity for clinically meaningful patient risk assessment.
Mujidat Jibrin, Abdsamad Benkrid
wiley +1 more source
Adeyinka Ashaye1, Ayodeji Arije2, Modupe Kuti3, Bolutife Olusanya1, Ezekiel Ayeni1, Adesoji Fasanmade4, Kehinde Akinlade3, Millicent Obajimi5, Jokotade Adeleye41Ophthalmology Department, College of Medicine, University of Ibadan, Nigeria; 2Renal Unit ...
Adeyinka Ashaye +5 more
core
Characteristics Analysis of Multifocal Electroretinogram in Non-proliferative Diabetic Retinopathy
Abstract Purpose To investigate multifocal electroretinogram (mfERG) changes in non-proliferative diabetic retinopathy (NPDR) patients compared to normal people, and to clarify the differences in changes across various regions of the retina. Methods We selected 18 healthy individuals (22 eyes) and 26 NPDR patients (45 eyes), using the RETscan
Ziwei Li, Yan Cui
openaire +1 more source

