Results 131 to 140 of about 617,984 (298)
Molecular Oncology, EarlyView.This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad +17 more
wiley +1 more source
GET SUBJECT SPORT -The Games We Used to Play An Application of Survival Analysis to the Sporting Life-course. ESRI WP272. January 2009 [PDF]
, 2009 In the absence of longitudinal data, recall data is used to examine participation in sport. Techniques of survival analysis are adapted and applied to illuminate the dynamics of sporting life. The likelihood of participation has a distinct pattern across
Lunn, Pete
core
Molecular Oncology, EarlyView.Genetic testing in epithelial ovarian cancer includes both germline and tumor‐testing. This approach often duplicates resources. The current prospective study assessed the feasibility of tumor‐first multigene testing by comparing tumor tissue with germline testing of peripheral blood using an 18‐gene NGS panel in 106 patients.
Elisabeth Spenard +12 more
wiley +1 more source
Generalized log-logistic proportional hazard model: a non-penalty shrinkage approach
, 2023 Quinn Forzley +2 more
openalex +2 more sources
A simulation study of the estimation quality in the double-Cox model with shared frailty for non-proportional hazards survival analysis [PDF]
, 2022 Alexander Begun, Elena Kulinskaya
openalex +1 more source
Molecular Oncology, EarlyView.Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard +5 more
wiley +1 more source
PCN288 APPLICATION OF THE LIFE EXPECTANCY RATIO AS A MEANINGFUL AND STATISTICALLY VALID MEASURE FOR NON-PROPORTIONAL HAZARDS INDIRECT COMPARISON META-ANALYSIS [PDF]
, 2020 Louis Dron, O. Bouldargi, Ofir Harari
openalex +1 more source
A Simple Test for the Absence of Covariate Dependence in Hazard Regression Models [PDF]
, 2004 This paper extends commonly used tests for equality of hazard rates in a two-sample or k-sample setup to a situation where the covariate under study is continuous.
Bhattacharjee, Arnab
core +4 more sources
Screening for lung cancer: A systematic review of overdiagnosis and its implications
Molecular Oncology, EarlyView.Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz +12 more
wiley +1 more source
Molecular Oncology, EarlyView.Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece +18 more
wiley +1 more source