Efficacy of modern antipsychotics in placebo-controlled trials in bipolar depression: a meta-analysis – results to be interpreted with caution [PDF]
, 2010 Randomized, controlled trials have demonstrated efficacy for second-generation antipsychotics in the treatment of acute mania in bipolar disorder. Despite depression being considered the hallmark of bipolar disorder, there are no published systematic ...
Goikolea, José Manuel +7 more
core +1 more source
The use of deception in public health behavioral intervention trials: a case study of three online alcohol trials. [PDF]
, 2013 Some public health behavioral intervention research studies involve deception. A methodological imperative to minimize bias can be in conflict with the ethical principle of informed consent.
Porter, John +7 more
core +1 more source
Frontiers in EndocrinologyObjectiveTo examine whether a theoretically grounded, 8-week physical literacy intervention incorporating salutogenic model components (sense of coherence, social support, and self-efficacy) could improve physical activity levels and clinical outcomes in
Guiyue Ma, Guiyue Ma
doaj +1 more source
Mirroring everyday clinical practice in clinical trial design: a new concept to improve the external validity of randomized double-blind placebo-controlled trials in the pharmacological treatment of major depression [PDF]
, 2012 Background: Randomized, double-blind, placebo-controlled trials constitute the gold standard in clinical research when testing the efficacy of new psychopharmacological interventions in the treatment of major depression.
Berger Michael +29 more
core +2 more sources
Pediatric Blood &Cancer, EarlyView.ABSTRACT Pediatric intramedullary low‐grade gliomas (PIMLGGs) are rare neoplasms that present unique clinical and management challenges. Although surgery remains the primary tool for tissue diagnosis and decompression, complete gross‐total resection is frequently unfeasible due to the infiltrative nature of these lesions.
Olga M. Sergeenko +5 more
wiley +1 more source
Evaluation of the effectiveness and cost-effectiveness of Families for Health V2 for the treatment of childhood obesity : study protocol for a randomized controlled trial [PDF]
, 2013 Background: Effective programs to help children manage their weight are required. Families for Health focuses on a parenting approach, designed to help parents develop their parenting skills to support lifestyle change within the family.
Petrou, Stavros +27 more
core +1 more source
Nurse-led randomized controlled trials in the perioperative setting: A scoping review [PDF]
, 2020 Purpose: Nurses provide care at each phase of the complex, perioperative pathway and are well placed to identify areas of care requiring investigation in randomized controlled trials.
Griffin, Bronwyn R. +20 more
core +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT The medical burdens of sickle cell disease (SCD) and transfusion‐dependent β‐thalassemia (TDT) are chronic and cumulative, even in children. Yet the effects expand beyond medications and healthcare visits due to their impacts on school attendance, academic performance, and peer engagement.
Mary Ann Etling +2 more
wiley +1 more source
International Journal of Infectious DiseasesBackground: Influenza pandemic plans often recommend non-pharmaceutical interventions (NPIs) in household settings, including hand hygiene and face masks.
Jessica Y. Wong +12 more
doaj +1 more source
Systematic Reviews, 2021 Background Rates of childhood obesity have accelerated rapidly over the past decade in low- and middle-income countries and in Latin America in particular.
Rachel Bleiweiss-Sande +4 more
doaj +1 more source