Results 241 to 250 of about 1,511,239 (338)

Knowledge, attitudes and current practices regarding LI-RADS^®: A survey from 14 countries in sub-Saharan Africa. [PDF]

SA J Radiol
Segobin R, Creamer D, Khan R, Jonas E, Sobnach S, Moosa S.   +5 more
europepmc   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source

Association between concomitant use of direct oral anticoagulants with antidepressants and an increased risk of hemorrhage: analysis of the food and drug administration adverse event reporting system database. [PDF]

Front Med (Lausanne)
Ran Y, Zhang Y, Cai Y, Liu H.
europepmc   +1 more source

Analyses pertaining to the reduction of non-specular scattering : technical report

, 1977
Thomas B. A. Senior
openalex   +1 more source

Analysis of Vibrations of Flexible Rotor by Integral Equation : 3rd Report, Non-Stationary Vibration through Critical Speed

, 1971
T. Kotera
openalex   +2 more sources

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

Molecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix, Daniel Samaga, Katharina Gehr, Benedek Dankó, Mohamed Schumann, Guido Drexler, Ahmed Alnatsha, Georg Beyer, Ujjwal Mahajan, Martin Selmansberger, Julia Mayerle, Claus Belka, Horst Zitzelsberger, Kirsten Lauber   +13 more
wiley   +1 more source

Evaluation of safety reporting in interventional trials of benign prostatic hyperplasia: a registry-publication comparison study. [PDF]

BMC Urol
Itani M, Livsey T, Keefer K, Elghzali A, Sherry R, Harris T, Archer D, Ford AI, Vassar M.   +8 more
europepmc   +1 more source

Non-Secretory Multiple Myeloma- A Diagnostic Dilemma: A Case Report

, 2017
Vijay Kumar, Lovleen Bhatia, Tarvinderjit Khurana, Amritpal Singh, Sanjay Goyal   +4 more
openalex   +1 more source