Results 51 to 60 of about 392,427 (260)
Elucidating Trainee Effect on Outcomes for General, Gynecologic, and Urologic Oncology Procedures
Journal of Investigative Surgery, 2017 Background and objectives: Surgical complications delay adjuvant therapy in oncology patients. Current literature remains unclear regarding resident effect on postoperative outcomes, with inappropriate coverage possibly endangering patients in spite of ...
Megan Sippey +2 more
doaj +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Taxation of Non – Resident Legal Entities in Romania. Case: Rmms vs. Anaf Brăila
Journal of Legal Studies, 2018 The taxation of non - resident economic entities supposes the establishment of an administrative framework as fair, efficient, effective and comprehensible as possible, fact due to the multifaceted nature of the concept of profits generated by an ...
Dumiter Professor Florin +1 more
doaj +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Sālmand, 2019 Objectives: The primary purpose of this study was to compare the social health and quality of life of the older people resident in nursing homes with non-resident elderlies in Tehran City, Iran, in 2015.
Mojgan Saeid +3 more
doaj
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
A rare case of Kikuchi-Fujimoto disease (case report)
Caspian Journal of Pediatrics, 2018 Background: Kikuchi disease is a rare, benign, self-limited disease characterized primarily by fever and cervical lymphadenopathy. Diagnosis is based on excisional biopsy and pathologic study.
Ahmad Tamaddoni +2 more
doaj
PATTERNS OF CONTACT AND INVOLVEMENT BETWEEN ADOLESCENTS AND THEIR NON-RESIDENT FATHERS
Social Work/Maatskaplike Werk, 2014 This study examined the patterns of contact and involvement between adolescents and their non-resident fathers after divorce. The data were analysed to determine the role of Lamb, Pleck and Levine’s (1986) three constructs in the involvement of non ...
Estelle De Wit, Dap Louw, Anet Louw
doaj +1 more source