Results 31 to 40 of about 7,703 (180)

DNA methylation profiles delineate epigenetic heterogeneity in seminoma and non-seminoma [PDF]

British Journal of Cancer, 2011
It remains important to understand the biology and identify biomarkers for less studied cancers like testicular cancer. The purpose of this study was to determine the methylation frequency of several cancer-related genes in different histological types of testicular cancer and normal testis tissues (NT).DNA was isolated from 43 seminomas (SEs), 14 non ...
Brait, M, Maldonado, L, Begum, S, Loyo, M, Wehle, D, Tavora, FF, Looijenga, LHJ (Leendert), Kowalski, J, Zhang, Z, Rosenbaum, E, Halachmi, S, Netto, GJ, Hoque, MO   +12 more
openaire   +3 more sources

Dataset of testicular germ cell tumors (TGCT) risk associated with serum polychlorinated biphenyl (PCB) by age at diagnosis and histologic types

Data in Brief, 2021
In a population-based case control study of testicular germ cell tumors (TGCT), we reported a strong positive association between serum levels of Wolff's Group 1 (potentially estrogenic) polychlorinated biphenyl (PCBs) and risk of TGCT, and the observed ...
Zhiyuan Cheng, Xichi Zhang, Bryan Bassig, Russ Hauser, Theodore R. Holford, Elizabeth Zheng, Dian Shi, Yong Zhu, Stephen Marc Schwartz, Chu Chen, Kunchong Shi, Bo Yang, Zhengmin Qian, Peter Boyle, Tongzhang Zheng   +14 more
doaj   +1 more source

Activin and BMP Signalling in Human Testicular Cancer Cell Lines, and a Role for the Nucleocytoplasmic Transport Protein Importin-5 in Their Crosstalk

Cells, 2023
Testicular germ cell tumours (TGCTs) are the most common malignancy in young men. Originating from foetal testicular germ cells that fail to differentiate correctly, TGCTs appear after puberty as germ cell neoplasia in situ cells that transform through ...
Karthika Radhakrishnan, Michael Luu, Josie Iaria, Jessie M. Sutherland, Eileen A. McLaughlin, Hong-Jian Zhu, Kate L. Loveland   +6 more
doaj   +1 more source

Redefining the IGCCCG classification in advanced non-seminoma

Annals of Oncology, 2019
Abstract Background The International Germ Cell Cancer Collaborative Group (IGCCCG) has been the reference classification for assessing prognosis in men with advanced non-seminomatous germ-cell tumors (NSGCT) for more than 20 years and it relied on 5202 cases treated between 1975 and 1990.
Gillessen, S., Collette, L., Daugaard, G., de Wit, R., Tryakin, A., Albany, C., Stahl, O., Fizazi, K., Gietema, J. A., De Giorgi, U. F. F., Hansen, A. R., Feldman, D., Cafferty, F., Tandstad, T., Garcia del Muro, X., Huddart, R. A., Sweeney, C. J., Heng, D. Y. C., Sauve, N., Beyer, J.   +19 more
openaire   +3 more sources

Oncological outcomes of testicular cancer patients: 10 years of experiences resulting from a single university-based hospital

Forum of Clinical Oncology, 2022
To explore clinical and pathological characteristics of testicular cancer and also identify factors associated with its oncological outcomes. Testicular cancer has a very good prognosis.
Bejrananda Tanan, Leetanaporn Komsan, Pruphetkaew Nannapat, Tanthanuch Monthira   +3 more
doaj   +1 more source

Retroperitoneal germ cell tumor, primary or secondary: A diagnostic conundrum

MGM Journal of Medical Sciences, 2023
Germ cell tumor, seminoma, is the most common cancer in young men’s testis. However, a small subset of tumors (1%–2%) originate in other locations and are referred to as primary extragonadal germ cell tumors. But such type of tumors’ origin is thought to
Surabhi Singh, Pranita Mohanty, Prateek Das, Debahuti Mohapatra, Pradyumna Kumar Sahoo   +4 more
doaj   +1 more source

Thirty-Year-Old Male Patient with Non-Seminoma and Coincidental Rectal Cancer

Urologia Internationalis, 2023
We present the case of a 31-year-old male patient with non-seminoma (90% embryonal carcinoma, 10% teratoma) pT1b L1 V0 Pn0 R0 cN2 cM0, Clinical Stage IIb and “good prognosis group” according to IGCCCG of the left testis. According to EAU guidelines, he received three cycles of BEP.
Julia Nolting, Desiree Louise Dräger, Oliver W. Hakenberg, Laila Schneidewind   +3 more
openaire   +2 more sources

Testicular seminoma relapse to the adrenal glands 25 years after primary diagnosis: A case report

Current Problems in Cancer: Case Reports, 2023
Testicular seminoma is a frequent tumor in young men, and most patients are cured after primary treatment. Relapse of the disease typically occurs within the first two years and late relapse after more than 5 years is only seen in around 4 %.
Christine Federspiel Secher, Thomas Wagner, Anand Chainsukh Loya, Gedske Daugaard, Jakob Lauritsen   +4 more
doaj   +1 more source

Antioxidant enzyme profile and lipid peroxidation products in semen samples of testicular germ cell tumor patients submitted to orchiectomy

International Brazilian Journal of Urology
Purpose To determine enzymatic antioxidant and lipid peroxidation levels in seminal plasma of patients orchiectomized for testicular tumors. Materials and Methods The study included 52 patients: 26 control men and 26 orchiectomized patients for ...
Camila Sposito, Mariana Camargo, Danielle Spinola Tibaldi, Valéria Barradas, Agnaldo Pereira Cedenho, Marcílio Nichi, Ricardo Pimenta Bertolla, Deborah Montagnini Spaine   +7 more
doaj   +1 more source

Two decades of FDG-PET/CT in seminoma: exploring its role in diagnosis, surveillance and follow-up

Cancer Imaging, 2022
Background Survivors of testicular cancer may experience long-term morbidity following treatment. There is an unmet need to investigate techniques that can differentiate individuals who need additional therapy from those who do not.
Ciara Conduit, Thuan Tzen Koh, Michael S Hofman, Guy C Toner, Jeremy Goad, Nathan Lawrentschuk, Keen-Hun Tai, Jeremy H Lewin, Ben Tran   +8 more
doaj   +1 more source