Results 81 to 90 of about 7,703 (180)

Involvement of epigenetic modifiers in the pathogenesis of testicular dysgenesis and germ cell cancer

Biomolecular Concepts, 2015
Testicular germ cell cancer manifests mainly in young adults as a seminoma or non-seminoma. The solid tumors are preceded by the presence of a non-invasive precursor cell, the carcinoma in situ cell (CIS), which shows great similarity to fetal germ cells.
Lawaetz Andreas C., Almstrup Kristian
doaj   +1 more source

Contrast‐enhanced ultrasonography vs MRI for indeterminate testicular lesions: a systematic review and meta‐analysis

BJU International, Volume 138, Issue 1, Page 57-67, July 2026.
Objective To conduct a systematic review and meta‐analysis to indirectly compare the diagnostic performance of contrast‐enhanced ultrasonography (CEUS) and magnetic resonance imaging (MRI) in the evaluation of indeterminate testicular lesions and to explore their potential roles in guiding clinical decision‐making.
Muhammed Arif Ibis, Maria Satchi, Nicholas Raison, Hakan Bahadır Haberal, Araz Musaev, Tet Yap, Angelo Territo, Cagri Akpinar, Giuseppe Fallara, Dean Y. Huang, Murat Gul, Asif Muneer, Antonio Ruffo, Omer Onur Cakir, Fabio Castiglione   +14 more
wiley   +1 more source

A meta-analysis of clinicopathologic features that predict necrosis or fibrosis at post-chemotherapy retroperitoneal lymph node dissection in individuals receiving treatment for non-seminoma germ cell tumours. [PDF]

Front Oncol, 2022
Conduit C, Hong W, Martin F, Thomas B, Lawrentschuk N, Goad J, Grimison P, Ahmadi N, Tran B, Lewin J.   +9 more
europepmc   +1 more source

Diagnostic yield of OCT3/4 reflex testing in testicular biopsy

Histopathology, Volume 89, Issue 1, Page 136-143, July 2026.
GCNIS detection frequency was 48/3353 (1.4%) testicular biopsies from 42/1870 (2.2%) men who underwent testicular biopsy with or without testicular sperm extraction (TESE). OCT3/4 was particularly helpful for detecting interstitial seminoma, GCNIS coexisting with mature spermatogenesis, and focal GCNIS.
Roselyne Choiniere, Willem PA Boellaard, Geert JLH van Leenders   +2 more
wiley   +1 more source

Genomic Profile in a Non-Seminoma Testicular Germ-Cell Tumor Cohort Reveals a Potential Biomarker of Sensitivity to Platinum-Based Therapy. [PDF]

Cancers (Basel), 2022
González-Barrios R, Alcaraz N, Montalvo-Casimiro M, Cervera A, Arriaga-Canon C, Munguia-Garza P, Hinojosa-Ugarte D, Sobrevilla-Moreno N, Torres-Arciga K, Mendoza-Perez J, Diaz-Chavez J, Cortes-González CC, Castro-Hernández C, Martínez-Cedillo J, Scavuzzo A, Pérez-Montiel D, Jiménez-Ríos MA, Herrera LA.   +17 more
europepmc   +1 more source

Deep exploration of the immune infiltrate and outcome prediction in testicular cancer by quantitative multiplexed immunohistochemistry and gene expression profiling

OncoImmunology, 2017
Platinum-based chemotherapy is usually curative for patients with testicular germ cell tumors (TGCT), but a subset of patients experience disease progression and poor clinical outcomes.
Peter J. Siska, Romany A. N. Johnpulle, Alice Zhou, Jennifer Bordeaux, Ju Young Kim, Bashar Dabbas, Naveen Dakappagari, Jeffrey C. Rathmell, W. Kimryn Rathmell, Alicia K. Morgans, Justin M. Balko, Douglas B. Johnson   +11 more
doaj   +1 more source

Rhabdomyosarcoma in Adults: De Novo or Conversion From Non-seminomas?

Cureus
Rhabdomyosarcoma (RMS) is a highly sporadic, very aggressive, and fatal soft tissue tumor in adults. Although more common and treatable in the pediatric population, the occurrence of pleomorphic RMS in adults has a low incidence. Hence, it is not easy to treat.
Ghrewati, Moutaz, Mahmoud, Anas, Beliani, Tala, Kumar, Mehandar   +3 more
openaire   +2 more sources

The PI3K/AKT Pathway Is Activated by HGF in NT2D1 Non-Seminoma Cells and Has a Role in the Modulation of Their Malignant Behavior. [PDF]

Int J Mol Sci, 2020
Gesualdi L, Leonetti E, Cucina A, Scicchitano BM, Sorrentino S, Tarsitano MG, Isidori A, Bizzarri M, Filippini A, Riccioli A, Cammarota M, Gigantino V, Ricci G, Catizone A.   +13 more
europepmc   +1 more source

Intratubular Non-Seminoma [PDF]

, 2020
openaire   +1 more source

Testicular Cancer Treatments and Sexuality: A Narrative Review

Medicina
The incidence of testicular cancer (TC) has been rapidly increasing over the past years. Diagnosis and early treatment have shown good oncological control, guaranteeing the patient different treatment approaches according to histology and tumor stage ...
Massimiliano Raffo, Angelo Di Naro, Luigi Napolitano, Achille Aveta, Simone Cilio, Savio Domenico Pandolfo, Celeste Manfredi, Chiara Lonati, Nazareno Roberto Suardi   +8 more
doaj   +1 more source