Results 201 to 210 of about 10,144,462 (296)

Engineering Morphological Anisotropy to Control the In Vivo Transport Dynamics, Clearance, and Biodistribution of Silica Nanocarriers

Advanced Science, EarlyView.
Morphological anisotropy directs the in vivo transport under physiological flow and clearance of silica nanocarriers. Increasing anisotropy reduces cellular uptake, suppresses hepatic and splenic sequestration, and prolongs systemic circulation by steering particles toward the central flow core.
Xiaofei Li, Yingjie Yu, Tianchang He, Xiaoyan Fang, Wenhua Yang, Luying Zhou, Hao Fan, Guimei Lin, Daniel Crespy, Katharina Landfester, Junfeng Zhang, Shuai Jiang   +11 more
wiley   +1 more source

Tailoring porosity and surface functionalization in nanoporous anodic alumina rugate filters for enhanced interferometric biosensing. [PDF]

Nanoscale Adv
Cantons JM, Formentin P, Ferré-Borrull J, Bachhuka A, Marsal LF.   +4 more
europepmc   +1 more source

Alternating Shear Force of Respiration Regulates Cell Interactions of Fibroblasts and Macrophages to Promote Soft Tissue Integration of Chest Wall Polyetheretherketone Implants

Advanced Science, EarlyView.
Given that PEEK chest wall implants induce shear force at the soft tissue‐implant interface due to respiratory motion in the early in vivo post‐implantation stage. We confirmed that this mechanical stimulus triggers the PIEZO1/ITGB1/YAP1 signalling axis in L929 and the STAT6/p‐STAT6 pathway in RAW264.7, which in turn mediates adhesion and migration of ...
Rou Huang, Yangfan Huo, Jin Liu, Sida Liu, Minghai Ma, Hao Guo, Yuanquan Zhang, Xing Li, Xiao Liang, Jiawei Xiu, Ying Sun, Lijun Huang, Xiaolong Yan, Weiwei Wu, Lei Wang   +14 more
wiley   +1 more source

Recurrent Juvenile Nasopharyngeal Angiofibroma: Two Cases Emphasizing the Role of Follow-Up and Staging in Surgical Planning. [PDF]

Int Med Case Rep J
Khaydarov M, Khudayorov M, Nazarov K, Abdurakhmonov O.   +3 more
europepmc   +1 more source

Multiphoton Quantum Reservoirs For Robust Multidimensional Computing

Advanced Science, EarlyView.
Projective measurements reveal hidden multidimensional quantum networks within classical multiphoton fields, enabling robust quantum reservoirs for room‐temperature quantum simulation, prediction, and information processing. These networks transform noisy classical photonic platforms into scalable quantum computational architectures.
Mingyuan Hong, Mario A. Quiroz‐Juarez, Riley B. Dawkins, Fatemeh Mostafavi, Jannatul Ferdous, Addison Wilberg, Blas M. Rodriguez‐Lara, Justin Woodring, Chenglong You, Roberto de J. León‐Montiel, Omar S. Magaña‐Loaiza   +10 more
wiley   +1 more source

Photophysical lock-in detection enables background-free upconversion emission imaging. [PDF]

Light Sci Appl
Bagheri N, Wang C, Guo D, Lakshmanan A, Zhu Q, Chen X, Ghazyani N, Zhan Q, Sotiriou GA, Liu H, Widengren J.   +10 more
europepmc   +1 more source

A Bioinspired, Multimodal Soft Tactile Skin with Task‐Adaptive Perception for Intelligent Robotic Manipulation

Advanced Science, EarlyView.
Perception in robotic manipulation improves through the cooperative and complementary operation of biologically inspired multimodal tactile sensors. Receptor‐specific contribution analysis identifies which sensing modalities are required for specific tactile tasks.
Yu‐Jin Lee, Hyeonung Kang, Ju Yeon Woo, Daekyum Kim, Chang‐Soo Han   +4 more
wiley   +1 more source

The Liver as a Biomarker Organ in Heart Failure: Molecular Mechanisms, Hepatic Scores and Systemic Risk Stratification. [PDF]

Int J Mol Sci
Szczurek-Wasilewicz W, Borowiec A, Waluszewska I, Szyguła-Jurkiewicz B.   +3 more
europepmc   +1 more source

Uncoupling Type I Interferon Benefits From Inflammatory Toxicity: Transformer‐Prioritized Precision Agonists for Potent and Safer Cancer Immunotherapy

Advanced Science, EarlyView.
A Transformer‐based AI framework, DLINP, screens millions of compounds to identify Co68, a cobalt‐pincer organometallic complex that biases TLR4‐MD2 signaling toward antitumor interferon activation while suppressing inflammatory toxicity through an early TLR4‐SYK‐STAT1 axis.
Xuefei Guo, Yang Zhao, Xianle Rong, Xingyu Chen, Xiao Wang, Tianyi Liu, Yunfei Xie, Yushu Zou, Pingsen Zhao, Qiang Liu, Fuping You   +10 more
wiley   +1 more source

Supramolecular Degraders: An Emerging Paradigm in Targeted Protein Degradation

Advanced Science, EarlyView.
Dynamic supramolecular assembly reshapes targeted protein degradation by coordinating modular degrader construction, delivery, functional integration, and intracellular assembly or activation across proteasomal, endosomal–lysosomal, and autophagy–lysosomal pathways.
Kongjun Liu, Xue Yuan, Yan Zhou, Rui Yuan, Shaocheng Xie, Yong Chen, Peiyi Wang, Jianmei Gao, Qihai Gong   +8 more
wiley   +1 more source