Results 91 to 100 of about 423,816 (314)

Rare case report: a case of histological type transformation of lung cancer caused by neoadjuvant immunotherapy

Frontiers in Oncology
Lung cancer remains the leading cause of cancer-related mortality, with 1.8 million deaths per year. Small cell lung cancer and non-small cell lung cancer (NSCLC) are the main cancer types.
Quanqing Li, Guangxin Zhang, Hao Yang, Jindong Li   +3 more
doaj   +1 more source

Smad3 is essential for polarization of tumor-associated neutrophils in non-small cell lung carcinoma

, 2023
Jeff Yat‐Fai Chung, Philip Chiu‐Tsun Tang, Max Kam‐Kwan Chan, Vivian Weiwen Xue, Xiao‐Ru Huang, Calvin S.H. Ng, Dongmei Zhang, Kam Tong Leung, Chun Kwok Wong, TL Lee, Eric W.‐F. Lam, David J. Nikolic‐Paterson, Ka‐Fai To, Hui Y. Lan, Patrick Ming‐Kuen Tang   +14 more
openalex   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

Comparison Study of Cyfra 21-1, Carcinoembryonic Antigen and Telomerase Activity between Non Small Cell and Small Cell Lung Cancer Patients

پزشکی بالینی ابن سینا, 2008
Introduction & Objective: The roles of tumor markers in the prognosis and diagnosis of lung cancer is under investigation. The aim of this study was to examine correlation between serum levels of Carcinoembryonic Antigen (CEA) and Cyfra 21-1 with ...
Behrang Alani, Khalil Ansarin, Mohammad Javad Selmizadeh, Ebrahim Cheraghi   +3 more
doaj  

Potential prognostic marker ubiquitin carboxyl-terminal hydrolase-L1 does not predict patient survival in non-small cell lung carcinoma [PDF]

, 2011
Katy S. Orr, Zhanzhong Shi, W. Mark Brown, Kathleen O’Hagan, Terence R.J. Lappin, Perry Maxwell, Melanie J. Percy   +6 more
openalex   +1 more source

Defining target volumes for non-small cell lung carcinoma

Seminars in Radiation Oncology, 2004
The definition of target volumes for non-small cell lung carcinoma (NSCLC) remains a controversial topic as tradition-based approaches of the past are being critically re-evaluated in the light of the advent of three-dimensional treatment techniques, by the awareness of the poor local control achieved using current treatment fields and radiation doses,
Senan, Suresh, Chapet, Olivier, Lagerwaard, Frank J., Ten Haken, Randall K.   +3 more
openaire   +4 more sources

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

An Unusual Primary Paraneoplastic Manifestation of Adenocarcinoma of Lung

Indian Journal of Clinical Cardiology
Carcinoma of lung (CoL) is the fourth most common cancer in India. It is classified as either small-cell or non-small-cell lung cancer, with adenocarcinoma being the most common variant.
Kartik Pandurang Jadhav, Bhulaxmi Pullikanti, Harish Kancharla, Pankaj V. Jariwala   +3 more
doaj   +1 more source

Multiple paraneoplastic syndromes revealing non-small cell lung carcinoma

Pan African Medical Journal, 2014
A broad spectrum of paraneoplastic dermatoses is associated with lung cancer. We report herein a 56-year-old man who presented an association of erythroderma, acquired ichthyosis, palmo-plantar keratoderma, hypereosinophilia and hyper IgE. In light of these clinical and biological assessments an underlying malignancy had been suspected.
Monia Youssef, Melek Kechida, Saoussen Cheikhmohamed, Adnene Moussa, Jameleddine   +4 more
openaire   +4 more sources

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

FEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan, Bethany C. Guerra, Selina Uranga, Jessica M. Cardin, Steven E. Riechman, Mariana Janini Gomes, James D. Fluckey   +6 more
wiley   +1 more source