Results 261 to 270 of about 623,894 (355)

Myomedin variants developed for in vitro PD-L1 diagnostics in tissue samples of non-small cell lung carcinoma patients. [PDF]

open access: yesJ Transl Med
Petroková H   +10 more
europepmc   +1 more source

Retinoic Acid Reprograms Mast Cells Toward a Proinflammatory State to Enhance Antitumor Immunity

open access: yesAdvanced Science, EarlyView.
Proinflammatory mast cells represent an MHC‐IIhigh, cytokine‐producing mast cell subset associated with improved survival and enhanced responses to anti‐PD‐1 therapy. Retinoic acid drives their polarization, enabling antigen uptake and presentation, and T cell recruitment and activation, collectively promoting adaptive anti‐tumor immunity.
Lizao Zhang   +25 more
wiley   +1 more source

Significance of DEK overexpression for the prognostic evaluation of non-small cell lung carcinoma

open access: bronze, 2015
Xin Liu   +7 more
openalex   +2 more sources

The Tumor‐to‐Endothelial Transfer of FTO Promotes Vascular Remodeling and Metastasis in Nasopharyngeal Carcinoma

open access: yesAdvanced Science, EarlyView.
Integrated omics analysis of matched primary and liver metastatic NPC tumors reveals a unique NOTCH1+ CSC subpopulation exhibiting enhanced stemness properties and tumorigenic capacity. With in vitro and in vivo assays, exosomal transfer of tumor‐derived FTO from NOTCH1+ cells to the endothelium promotes vascular permeability and metastatic potential ...
Chun Wu   +23 more
wiley   +1 more source

Clinofibrate Disrupts the SNORA80B/YTHDC1‐Driven M6A Modification to Suppress Cholesterol Metabolism and Cisplatin Resistance in ESCC

open access: yesAdvanced Science, EarlyView.
This study uncovers a non‐canonical role of SNORA80B in ESCC, showing it mediates AR‐driven metabolic reprogramming via N⁶‐methyladenosine (m6A) methylation. By binding YTHDC1, SNORA80B stabilizes cholesterol‐metabolic enzyme mRNAs and promotes tumor progression. The FDA‐approved drug clinofibrate inhibits SNORA80B by disrupting cholesterol homeostasis,
Hongyu Yuan   +7 more
wiley   +1 more source

Prognostic Indicators for Precision Treatment of Non-Small Cell Lung Carcinoma. [PDF]

open access: yesCells
Ghosh DD   +8 more
europepmc   +1 more source

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