Results 41 to 50 of about 623,894 (355)

Lung cancer: risk factors, management, and prognosis [PDF]

, 2016
Lung cancer or lung tumor the most common cause of cancer death in men and second most common in women after breast cancer. Highest rates in North America, Europe, and East Asia, with one third of new cases in China, lower rates in Africa and South Asia.
A. Nazirah, AM, Sharifa, AR. Jamalul Azizi, EL. IIIzam, Murtaza Mustafa, SA. Abbas   +5 more
core   +1 more source

RET in non-small cell lung carcinoma

Cancer Research, Statistics, and Treatment, 2021
The advent of stratified medicine and tailored therapies has caused non-small cell lung cancer (NSCLC) to become a subject of keen interest, with an emphasis on comprehensive genomic testing for driver mutations and biomarkers. The rearranged during transfection (RET) gene rearrangement has been observed in 1%–2% of all NSCLCs.
Shrinidhi Nathany, Himanshi Diwan, Ullas Batra   +2 more
openaire   +1 more source

Histological transformation of adenocarcinoma to small cell carcinoma lung as a rare mechanism of resistance to epidermal growth factor receptor-tyrosine kinase inhibitors: Report of a case with review of literature

Lung India, 2018
A subset of non-small cell lung carcinoma (NSCC) harbor active mutations of epidermal growth factor receptor (EGFR). In these, EGFR tyrosine kinase inhibitors (EGFR-TKIs) are recommended as the first-line treatment.
Monalisa Hui, Shantveer G Uppin, Bala Joseph Stalin, G Sadashivudu   +3 more
doaj   +1 more source

MAP17 predicts sensitivity to platinum-based therapy, EGFR inhibitors and the proteasome inhibitor bortezomib in lung adenocarcinoma [PDF]

, 2018
Background The high incidence and mortality of lung tumours is a major health problem. Therefore, the identification both of biomarkers predicting efficacy for therapies in use and of novel efficacious therapeutic agents is crucial to increase patient ...
Carnero Moya, Amancio, Ferrer, Irene, García Heredia, José Manuel, Molina Pinelo, Sonia, Pérez, Marco, Quintanal Villalonga, Álvaro Diego   +5 more
core   +1 more source

Study of PD-L1 Expression in Tumours Based on Site and Histology of Tumour – The Experience of a Tertiary Referral Laboratory

Asian Pacific Journal of Cancer Biology, 2023
Background: PD-L1 IHC test is used as a predictive biomarker using FDA-approved assays to select patients likely to benefit from immunotherapy in several advanced-stage tumors. We aim to present our data regarding the prevalence and expression pattern of
Vinita Pant, Munmun Harlalka
doaj   +1 more source

The Diagnostic Accuracy of Chest CT in the Detection of Tumor and Nodal Status in Non Small Cell Lung Carcinoma [PDF]

, 2003
At this time there is an increasing demand for an accurate pre operative staging in non small cell lung cancer. Chest Computed Tomography (CT) is one of the imaging modality of choice used for this purpose.
Busroh, I. (Ismid), Icksan, A. (Aziza), Syachruddin, E. (Elisna), Yusuf, A. (Anwar)   +3 more
core   +1 more source

Induction S-1+Concurrent Radiotherapy Followed by Surgical Resection of Locally Advanced Non-small-cell Lung Cancer in an Elderly Patient [PDF]

, 2016
We present the case of a 77-year-old Japanese man diagnosed with lung squamous cell carcinoma with mediastinal lymph node metastasis. He was treated with induction chemoradiotherapy for T1bN2M0 stage IIIA disease.
Katsui, Kuniaki, Kiura, Katsuyuki, Maki, Yuho, Miyoshi, Shinichiro, Soh, Junichi, Torigoe, Hidejiro, Toyooka, Shinichi   +6 more
core   +1 more source

Psychosocial Outcomes in Patients With Endocrine Tumor Syndromes: A Systematic Review

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction The combination of disease manifestations, the familial burden, and varying penetrance of endocrine tumor syndromes (ETSs) is unique. This review aimed to portray and summarize available data on psychosocial outcomes in patients with ETSs and explore gaps and opportunities for future research and care.
Daniël Zwerus, Floortje Strobbe, Annemarie A. Verrijn Stuart, Hanneke M. van Santen, Gerlof D. Valk, Sasja A. Schepers, Rachel S. van Leeuwaarde   +6 more
wiley   +1 more source

Transdifferentiation of lung adenocarcinoma in mice with Lkb1 deficiency to squamous cell carcinoma [PDF]

, 2014
Lineage transition in adenocarcinoma (ADC) and squamous cell carcinoma (SCC) of non-small cell lung cancer, as implicated by clinical observation of mixed ADC and SCC pathologies in adenosquamous cell carcinoma, remains a fundamental yet unsolved ...
Chen, Haiquan, Fang, Jing, Fang, Rong, Fang, Zhaoyuan, Gao, Yijun, Ge, Gaoxiang, Han, Xiangkun, Hou, Yingyong, Ji, Hongbin, Li, Fei, Li, Fuming, Li, Li, Ma, Huimin, Sun, Yihua, Wang, Hongda, Wong, Kwok-kin, Xiao, Qian, Yao, Shun, Zhang, Lei, Zhang, Wenjing   +19 more
core   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source