Results 61 to 70 of about 623,894 (355)

Stereotactic ablative radiotherapy for medically inoperable early stage lung cancer: early outcomes [PDF]

, 2012
Objective To evaluate the clinical outcome and safety of stereotactic ablative radiotherapy for medically inoperable stage I non- small-cell lung carcinoma. Design Retrospective case series.
Chan, Connie C C, Chan, Oscar S H, Chang, Amy T Y, Hung, Albert W M, Lee, Anne W M, Lee, Michael C H, Yeung, Rebecca M W   +6 more
core  

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

Molecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts, Senada Koljenović, Elise Daems, Karolien De Wael, Marc Peeters, Léon C. van Kempen, Greetje Vanhoutte, Karen Zwaenepoel, Timon Vandamme   +8 more
wiley   +1 more source

Blood-Derived Exosomal hTERT mRNA in Patients with Lung Cancer: Characterization and Correlation with Response to Therapy

Biomedicines, 2023
Background: Telomerase (human telomerase reverse transcriptase (hTERT) is considered a hallmark of cancer, being active in cancer cells but repressed in human somatic cells. As such, it has the potential to serve as a valid cancer biomarker.
Ofer Rotem, Alona Zer, Lilach Yosef, Einat Beery, Hadar Goldvaser, Anna Gutkin, Ron Levin, Elizabeth Dudnik, Tamar Berger, Meora Feinmesser, Adva Levy-Barda, Meir Lahav, Pia Raanani, Orit Uziel   +13 more
doaj   +1 more source

Arsenic trioxide suppresses tumour growth in squamous cell lung carcinoma [PDF]

, 2015
This journal suppl. entitled: 20th Medical Research Conference; Department of Medicine, The University of Hong Kong, Queen Mary Hospital, Hong KongINTRODUCTION: Squamous cell lung carcinoma (SCC) belongs to the second most common subtype in non–small ...
Ho, JCM, Lam, SK, Leung, LL
core  

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira, Anna Skwarska, Karolina Chwialkowska, Agnieszka Ostrowska, Gabriela Sokolowska, Anna Zeller, Anna Erol, Andrzej Eljaszewicz, Bartosz Hanczaruk, Anna Michalska‐Falkowska, Agnieszka Tarasik, Joanna Reszec‐Gielazyn, Pawel Knapp, Marcin Moniuszko, Adam Kretowski   +14 more
wiley   +1 more source

Current status of EGFR/ErbB inhibitors in non-small cell lung carcinoma [PDF]

, 2016
Durante los últimos 10 años hemos asistido a un cambio importante en el tratamiento del cáncer de pulmón (CP). El descubrimiento en 2004 de las mutaciones activadoras del receptor del factor de crecimiento epidérmico (EGFR) en alguno de los subgrupos ...
Esteban González, Emilio, Álvarez Fernández, Carlos   +1 more
core   +1 more source

TTF-1/p63-positive poorly differentiated NSCLC: A histogenetic hypothesis from the basal reserve cell of the terminal respiratory unit [PDF]

, 2020
TTF-1 is expressed in the alveolar epithelium and in the basal cells of distal terminal bronchioles. It is considered the most sensitive and specific marker to define the adenocarcinoma arising from the terminal respiratory unit (TRU). TTF-1, CK7, CK5/6,
Barraco N., Bellavia S., Cabibi D., Cajozzo M., Cipolla C., Florena A. M., Giannone A. G., Martorana A., Rodolico V.   +8 more
core   +1 more source

Drug Resistance Mechanisms in Non-Small Cell Lung Carcinoma [PDF]

Journal of Cancer Research Updates, 2013
Lung cancer is the most commonly diagnosed cancer in the world. “Driver” and “passenger” mutations identified in lung cancer indicate that genetics play a major role in the development of the disease, progression, metastasis and response to therapy.
Wangari-Talbot, Janet, Hopper-Borge, Elizabeth   +1 more
openaire   +2 more sources

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

Molecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy, Samuel Hartzler, Paula A. Vargas Carranza, Shyaman Jayasundara, Madison E. Yates, Nimod D. Janson, Bozhi Liu, Annaleigh Benton, Majid Kazemian, Jason A. Hanna   +9 more
wiley   +1 more source

Long-term survival after an aggressive surgical resection and chemotherapy for stage IV pulmonary giant cell carcinoma [PDF]

, 2005
BACKGROUND: Pulmonary giant cell carcinoma is one of the rare histological subtypes with pleomorphic, sarcomatoid or sarcomatous elements. The prognosis of patients with this tumor tends to be poor, because surgery, irradiation and chemotherapy are not ...
Ichinose, Yukito, Ikeda, Jiro, Maruyama, Riichiroh, Nakamura, Tomomi, Okamoto, Tatsuro, Shoji, Fumihiro, Wataya, Hiroshi   +6 more
core   +3 more sources