Results 251 to 260 of about 346,212 (321)
Antiviral Inactivated Vaccines: Looking to the Past to Face the Future-A Narrative Review. [PDF]
Guedes-da-Silva FH +7 more
europepmc +1 more source
Depletion of the RNA‐Editing Enzyme ADAR1 Invigorates the Antitumor Immunity of NK Cells
ADAR1 is upregulated in NK cells from melanoma patients, impairing their function. Its loss enhances NK cell tumor infiltration and cytotoxicity in vitro and in vivo. Mechanistically, ADAR1 deficiency destabilizes CD38 mRNA to reduce its expression, thereby increasing NK cell mobility and killing, which nominates it as a therapeutic target for NK cell ...
Shuhan Chen +11 more
wiley +1 more source
Vaccination Against Respiratory Infections in Adults with Cancer: A Concise Guide for Clinicians. [PDF]
See KC.
europepmc +1 more source
We present a novel DNA vaccine platform featuring intrinsic, non‐targeting dsRNA that significantly enhances immune responses by activating the regulated IRE1‐dependent decay‐RIG‐I signaling pathway. This research elucidates a previously uncharacterized mechanism for dsRNA‐mediated innate immune activation.
Min‐Syuan Huang +10 more
wiley +1 more source
Circular RNAs: roles in hepatocellular carcinoma immune regulation, implications in immunotherapy, and prospects for clinical translation. [PDF]
Chen Y +6 more
europepmc +1 more source
Nanoparticle Immunoadjuvant Complexes Augment Germinal Center Responses to Vaccination
Scaffolding IL‐21 on the surface of a self‐assembling nanoparticle immunogen drives improved germinal center and humoral immune responses. These nanoparticle immunoadjuvant complexes (NICs) functionally modulate the germinal center driving improved somatic hypermutation and antibody maturation, suggesting this platform has potential utility as a ...
Nicholas J. Tursi +21 more
wiley +1 more source
Human anthrax vaccines: Current status and future prospects. [PDF]
Qiao Z +6 more
europepmc +1 more source
Typology of interventions to reduce use of antimicrobials in aquaculture systems in low- and middle- income countries [PDF]
Garza, Maria +3 more
core

