Results 271 to 280 of about 346,212 (321)

Effectiveness of Pre‐Transplant Dual GLP‐1 Receptor Agonist and SGLT2 Inhibitor Therapy on All‐Cause Mortality in Organ Transplantation Candidates with Obesity and Type 2 Diabetes: a Target‐Trial Emulation

Advanced Science, EarlyView.
This target trial emulation in solid organ transplant candidates with obesity and type 2 diabetes evaluates whether pre‐transplant dual therapy with GLP‐1 receptor agonists plus SGLT2 inhibitors is associated with post‐transplant mortality and kidney graft outcomes compared with monotherapy or usual care, using multinational electronic health records ...
Yu‐Nan Huang, Min‐Yu Tsou, Pin‐Hung Li, Jo‐Ching Chen, Yen‐Liang Liu, Gideon Meyerowitz‐Katz, Tsung‐Hsun Tsai, Pen‐Hua Su   +7 more
wiley   +1 more source

The effect of BCG vaccination on adult mortality during the COVID-19 pandemic: a meta-analysis of randomised controlled trials

Schaltz-Buchholzer F, Curtis N, Diacon AH, Giamarellos-Bourboulis EJ, Kotsaki A, Rosendahl Madsen AM, Messina NL, Nhamússua L, Nielsen S, Pittet LF, da Silva I, Sparrow A, Upton C, van Werkhoeven C, Netea MG, Benn CS, Aaby P.   +16 more
europepmc   +1 more source

Nanovaccines in gastrointestinal cancers. [PDF]

Front Immunol
Wang Y, Huang P, Li C, Tu S, Yang H.
europepmc   +1 more source

CD147/Basigin: From Integrative Molecular Hub to Translational Therapeutic Target

Advanced Science, EarlyView.
This review conceptualizes CD147 as a fundamental “Energy‐Structure Coupler,” physically bridging metabolic flux (via MCTs) with morphogenetic plasticity (via integrins/MMPs) to drive cancer, infection, and autoimmunity. Addressing the “specificity paradox” that limits current translation, the authors chart a strategic roadmap—spanning logic‐gated ...
Xiang‐Min Yang, Huijie Bian, Zhi‐Nan Chen   +2 more
wiley   +1 more source

Vaccination in Children with Chronic Kidney Disease: Current Status and Perspectives. [PDF]

Vaccines (Basel)
Bitsori M, Michailou M, Galanakis E.
europepmc   +1 more source

Trojan Horse Strategy: How Biomimetic Nanomedicine Remodels the Tumor Microenvironment

Advanced Science, EarlyView.
This review focuses on biomimetic nanomedicines for tumor microenvironment (TME) remodeling, covering their diverse biomimetic types, design principles, and mechanisms of immune cell reprogramming and reversal of immunosuppressive microenvironments, with particular emphasis on their application in synergistic immunotherapy.
Wanrong Wang, Siqi Mu, Juan Zhang, Guisong Shan, Xueqian Li, Ran Wang, Tao Guo, Xiaoyan He   +7 more
wiley   +1 more source

mRNA vaccines: immunogenicity and quality characteristics. [PDF]

J Nanobiotechnology
Quan Y, Yang H, Li W, Li L.
europepmc   +1 more source

Stereoselective Ferrier‐Type O‐Glycosylation Enabled by Difluoromethylated Glycal Donors

Advanced Science, EarlyView.
A fluorine‐mediated stereoselective Ferrier‐type glycosylation is reported. Glycals are pre‐decorated with photo‐2‐difluoroalkylation and reacted with diverse acceptors to obtain exclusively α‐selective Ferrier rearrangement products. Abstract The effective construction of structurally homogeneous glycosides is requisite in oligosaccharide assembly and
You Zou, Hengfu Xu, Cang‐Xin Zheng, Weiwei Zhang, Xin‐Shan Ye, De‐Cai Xiong   +5 more
wiley   +1 more source

Preclinical Assessment of a New Virus-like Particle-Based Quadrivalent Human Papillomavirus Vaccine in Animal Models. [PDF]

Vaccines (Basel)
Mohammadi Barzelighi H, Naderi Saffar Z, Pakatchian E, Taqavian M, Javadimehr B, Safaeian M, Abbaszadeh P, Jalili H.   +7 more
europepmc   +1 more source