Results 141 to 150 of about 121,857 (258)

A multifaceted interplay between hemophagocytosis, IL‐18 and type I IFN distinguishes Still disease from other autoinflammatory diseases

Arthritis &Rheumatology, Accepted Article.
Objectives The unknown pathophysiology and the lack of specific features for systemic Juvenile Idiopathic arthritis and adult‐onset Still disease (collectively Still disease/SD) delays diagnosis and appropriate treatment. The goal of this study was to identify features and mechanisms that distinguish SD from other systemic autoinflammatory diseases ...
Yvonne M. Mueller, Charlotte Girard, Harmen J. G. van de Werken, Stefan J. Erkeland, Dwin G.B. Grashof, Laurie Vaillant, Renske J.H. den Dekker, Iris van Zuijen, Sharon Veenbergen, Fanny Coffin, Eric Bindels, Yvan Jamilloux, Katerina Laskari, ImmunAID consortium, Vassili Soumelis, Bruno Fautrel, Cem Gabay, Peter D. Katsikis   +17 more
wiley   +1 more source

Non-specific neck pain evaluation using functional linear models with the limma correction. [PDF]

Med Biol Eng Comput
Aragón-Basanta E, Ayala G, Page Á, Serra-Añó P.   +3 more
europepmc   +1 more source

Biological/targeted synthetic DMARDs do not arrest bone loss in patients with rheumatoid arthritis: a long‐term multicenter observational study

Arthritis &Rheumatology, Accepted Article.
Objective Osteoporosis causes fractures which further increase the disease burden of rheumatoid arthritis (RA), however, osteoporosis treatment rates remain low. While several studies have reported that biologic or targeted synthetic disease‐modifying antirheumatic drugs (b/tsDMARDs) can prevent or improve osteoporosis in RA, our large‐scale, real ...
Takafumi Aritomi, Koshiro Sonomoto, Shingo Nakayamada, Hiroaki Tanaka, Atsushi Nagayasu, Satoshi Kubo, Ippei Miyagawa, Ayako Yamaguchi, Naoaki Ohkubo, Yasuyuki Todoroki, Yurie Satoh‐Kanda, Masanobu Ueno, Ryuichiro Kanda, Yuya Fujita, Masashi Funada, Hidenori Sakai, Satsuki Matsunaga, Hiroaki Tanaka, Masayuki Shinojima, Hiroki Kawamura, Kazuki Takahashi, Miyabi Ando, Kazuki Haru, Yusuke Miyazaki, Kentaro Hanami, Masao Nawata, Shunsuke Fukuyo, Keisuke Nakatsuka, Mikiko Tokunaga, Kazuyoshi Saito, Yoshiya Tanaka   +30 more
wiley   +1 more source

The impact of catastrophic thinking on postural stability in individuals with chronic non-specific neck pain: a cross-sectional study in a clinical setting. [PDF]

BMJ Open
Alshahrani MS, Reddy RS, Alnakhli HH.
europepmc   +1 more source

Navigating adverse immunostimulation: A practical guide for clinical researchers

British Journal of Clinical Pharmacology, EarlyView.
Problem Setting As drug development moves towards more complex products, early clinical development programmes are increasingly hampered by unwanted and/or unexpected activation of the immune system (adverse immune stimulation, AIS). Solution At the Centre for Human Drug Research, we have introduced standardized procedures to make AIS manageable, while
Juliette A. van den Noort, Anouk C. Meijs, Naomi B. Klarenbeek, Matthijs Moerland   +3 more
wiley   +1 more source

Assessing the viability of heart rate variability as an objective and comprehensive indicator of chronic non-specific neck pain. [PDF]

PLoS One
Zhang C, Xu HP, Zheng HF, Wu XL, Du HG, Jin X.   +5 more
europepmc   +1 more source

Population pharmacokinetic modelling of amoxicillin in human breast milk—A contribution from the ConcePTION project

British Journal of Clinical Pharmacology, EarlyView.
Aims Amoxicillin, a widely used β‐lactam antibiotic, requires improved pharmacokinetic characterization during breastfeeding. This study used a population pharmacokinetic (PopPK) approach to model amoxicillin concentrations in breast milk, identify variability sources and estimate infant exposure, applying worst‐case scenarios.
Sarah Baklouti, Virginie Rigourd, Alice Panchaud, Hedvig Nordeng, Karel Allegaert, Pieter Annaert, Miao‐Chan Huang, Anaelle Monfort, Monia Guidi, Peggy Gandia   +9 more
wiley   +1 more source

Multi-wave locked system laser therapy in chronic non-specific neck pain: a double-blind placebo randomized-controlled trial. [PDF]

Eur J Phys Rehabil Med
Labanca L, Platano D, Tedeschi R, Cappelli E, Benedetti MG, Berti L.   +5 more
europepmc   +1 more source

Effectiveness of Telerehabilitation Exercise Programme on Disability and Pain in Patients With Chronic Non-Specific Neck Pain: Randomised Controlled Trial Assessor-Blinded. [PDF]

Musculoskeletal Care
Barbosa JC, da Luz BV, da Silva BFP, Marques AP, Saragiotto BT, Comachio J, Magalhaes MO.   +6 more
europepmc   +1 more source

Effect of osteopathic manipulation on neck kinematics using X-Sens motion capture in non-specific neck pain: a protocol for randomised controlled trial. [PDF]

BMJ Open Sport Exerc Med
Hullumani S, Qureshi I, Raghumahanti R.
europepmc   +1 more source