Results 71 to 80 of about 441,080 (294)

Plasma anisotropy around non-spherical conductive dust particle

Physical Sciences and Technology, 2019
This paper presents a computational model that allows self-consistent simulation of plasma distributions around isolated strongly charged dust grains with different geometries: spherical, ellipsoidal, and diskshaped dust particles. All particles in this
G. Sukhinin, М. Salnikov, А. Fedoseev
doaj  

Kinetic energy functional for Fermi vapors in spherical harmonic confinement

, 2001
Two equations are constructed which reflect, for fermions moving independently in a spherical harmonic potential, a differential virial theorem and a relation between the turning points of kinetic energy and particle densities.
A. Minguzzi, Brack, DeMarco, Holland, Lawes, M.P. Tosi, March, March, Mewes, Morse, N.H. March, Schreck, von Weizsäcker   +12 more
core   +2 more sources

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Consolidation of Non-Colloidal Spherical Particles at Low Particle Reynolds Numbers

KONA Powder and Particle Journal, 2015
When a system of identical spheres settles under conditions of negligible surface and inertial forces an idealised form of sediment consolidation unfolds amenable to a universal description.
Kevin P. Galvin, Marveh Forghani, Elham Doroodchi, Simon M. Iveson   +3 more
doaj   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Symmetry constraints for the emission angle dependence of Hanbury Brown--Twiss radii

, 2002
We discuss symmetry constraints on the azimuthal oscillations of two-particle correlation (Hanbury Brown--Twiss interferometry) radii for non-central collisions between equal spherical nuclei.
A. Hummel, A.M. Poskanzer, H. Stöcker, J.Y. Ollitrault, J.Y. Ollitrault, M. A. Lisa, M.A. Lisa, M.A. Lisa, S. Chapman, S. Chapman, S. Voloshin, S.A. Voloshin, S.A. Voloshin, U. A. Wiedemann, U. Heinz, U. Heinz, U. Heinz, U. Heinz, U.A. Wiedemann, U.A. Wiedemann   +19 more
core   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Coagulation Characteristics of Nano-agglomerates in Free Molecular States under Different Electric Field Intensities

Aerosol and Air Quality Research
The coagulation behavior of nanoparticles in microfluidic chip channels is complex and affected by various external factors, including electric fields, sound fields, and wakes.
Ting Luo, Pengfei Zhang, Dongxu Cheng, Congcong Li, Junyi Shen, Mingyue Yang, Jie Zhao, Kai Zhang, Qianyuan Yu, Zhandong Shi   +9 more
doaj   +1 more source