Results 191 to 200 of about 109,707 (304)

CYP2C19 genotype testing for clopidogrel: A guideline developed by the UK Centre of Excellence in Regulatory Science and Innovation in Pharmacogenomics (CERSI‐PGx)

open access: yesBritish Journal of Clinical Pharmacology, Volume 92, Issue 2, Page 329-347, February 2026.
Clopidogrel, an antiplatelet agent, is currently licensed in the United Kingdom for the prevention and treatment of atherothrombotic events in cerebrovascular disease, coronary artery disease and peripheral arterial disease. Clopidogrel requires metabolic activation by the cytochrome P450 enzyme CYP2C19 to be effective.
Cinzia Dello Russo   +22 more
wiley   +1 more source

Association of Sleep Disturbance With Survival After Colorectal Cancer Diagnosis: Results From the ColoCare Study

open access: yesCancer Medicine, Volume 15, Issue 2, February 2026.
ABSTRACT Introduction Sleep problems are common among cancer patients. The relationship between sleep disruption and clinical outcomes after colorectal cancer (CRC) diagnosis remains poorly understood. We investigated associations of sleep disruption with survival and recurrence in patients with CRC. Methods CRC patients with stages I–IV (N = 895) were
Anita R. Peoples   +18 more
wiley   +1 more source

OCT‐Guided Distal Left Main Bifurcation PCI: Mid‐Term Outcomes From a Multicenter South‐Asian Registry

open access: yesCatheterization and Cardiovascular Interventions, Volume 107, Issue 2, Page 477-484, February 1, 2026.
ABSTRACT Background Optical coherence tomography (OCT)‐guided percutaneous coronary intervention (PCI) enhances treatment of complex coronary artery lesions, including left main (LM) disease, by enabling lesion morphology assessment and stent optimization, thereby reducing major adverse cardiac events (MACE).
Prathap Kumar   +4 more
wiley   +1 more source

Plasma expression of lncRNA Wisper in patients with heart failure and patients with myocardial infarction. [PDF]

open access: yesFuture Cardiol
Doneva JG   +8 more
europepmc   +1 more source

Nationwide Analysis of PCI After TAVR From the Netherlands Heart Registration

open access: yesCatheterization and Cardiovascular Interventions, Volume 107, Issue 3, Page 824-832, February 15, 2026.
ABSTRACT Background Percutaneous coronary intervention (PCI) after transcatheter aortic valve replacement (TAVR) has gained interest as concomitant coronary artery disease (CAD) is now often treated conservatively before TAVR, and TAVR is increasingly used in younger patients with longer life expectancies. Therefore, more contemporary data on PCI after
Hugo M. Aarts   +7 more
wiley   +1 more source

Simultaneous Intracranial and Spinal Hemorrhage Following Tenecteplase Thrombolysis for ST‐Elevation Myocardial Infarction: A Case Report

open access: yesClinical Case Reports, Volume 14, Issue 2, February 2026.
ABSTRACT Central nervous system (CNS) hemorrhage is a serious complication of intravenous thrombolysis. Tenecteplase, a fibrin‐specific thrombolytic agent, has a lower risk of hemorrhage than other agents. We report the first documented case of simultaneous intracranial and spinal hemorrhage following intravenous administration of tenecteplase.
Thamalee Palliyaguru   +4 more
wiley   +1 more source

Drug‐Resistant Sinus Tachycardia as a Dose‐Dependent Side Effect of Spironolactone: A Case Report and Review of the Literature

open access: yesClinical Case Reports, Volume 14, Issue 2, February 2026.
ABSTRACT Spironolactone is widely used for polycystic ovarian syndrome due to its anti‐androgenic properties. However, rare cardiovascular side effects may occur even in normotensive patients. We report a case of severe palpitations and drug‐resistant sinus tachycardia following high‐dose therapy, emphasizing the need for cautious titration and cardiac
Zahra Abdi   +3 more
wiley   +1 more source

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