Results 231 to 240 of about 13,194,152 (302)

Exosomal let‐7c‐5p From AMI Patient Plasma Modulates Neuronal PANoptosis via ZBP1 In Vitro

open access: yesCell Biochemistry and Function, Volume 44, Issue 10, October 2026.
ABSTRACT Acute myocardial infarction (AMI) significantly elevates the risk of ischemic stroke (IS), yet the molecular mechanisms linking cardiac and cerebral injury remain unclear. Emerging evidence highlights the role of circulating exosomes in mediating inter‐organ communication via microRNAs (miRNAs). In this study, plasma exosomes from AMI patients
Zhiyong Zhang   +11 more
wiley   +1 more source

National and Subnational Trends in Ischemic Heart Disease Burden in Iran, 1990–2023: A Systematic Review

open access: yesClinical Cardiology, Volume 49, Issue 10, October 2026.
In Iran, age‐standardized ischemic heart disease mortality and incidence declined from 1990 to 2019, while absolute incident cases increased substantially. Burden remained higher in men and older adults, with marked provincial variation, highlighting the need for stronger prevention and more standardized national surveillance.
Mehrdad Rabiee Rad   +12 more
wiley   +1 more source

SGLT2i in heart failure: Cardiorenal mechanisms, clinical evidence and translational perspectives

open access: yesClinical and Translational Discovery, Volume 6, Issue 5, October 2026.
SGLT2 inhibitors improve heart failure outcomes through integrated cardiorenal mechanisms. In the kidney, they reduce glucose and sodium reabsorption, promoting natriuresis, osmotic diuresis and renal protection. In the heart, they enhance myocardial energetics, reduce inflammation, oxidative stress, fibrosis and adverse remodelling, resulting in fewer
Jelica Grujic‐Milanovic   +4 more
wiley   +1 more source

After delivery: How recipient cells shape the fate and function of transplanted mitochondria

open access: yesClinical and Translational Medicine, Volume 16, Issue 10, October 2026.
Recipient‐cell handling shapes how transplanted mitochondria contribute after delivery, linking donor competence, recipient state and exposure duration to intracellular fate. The framework matches transient rescue, sustained functional support and durable mitochondrial DNA correction to the evidence and product attributes required for each therapeutic ...
Zhi‐Yuan Zhang   +3 more
wiley   +1 more source

Dietary Carotenoids and Cognitive Decline: A Longitudinal Study Among Chinese Middle‐Aged and Older Adults

open access: yesHealth Care Science, Volume 5, Issue 5, Page 415-423, October 2026.
Higher intake of dietary carotenoids was associated with slower cognitive decline. The strongest protective association was observed for moderate carotenoid intake. Total carotenoid intake exhibited a non‐linear association with cognitive decline. ABSTRACT Background This study examined the association between dietary intakes of total and specific ...
Liyan Huang   +9 more
wiley   +1 more source

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