ANZ Journal of Surgery, EarlyView.Among 223 patients with appendiceal high‐grade pseudomyxoma peritonei, a high advanced lung cancer inflammation index (ALI) was independently associated with improved overall survival. A nomogram integrating ALI with clinicopathological and surgical factors showed good discrimination, calibration, and clinical utility for predicting 1‐, 2‐, and 3‐year ...
Yun Gao +4 more
wiley +1 more source
Divergent management of a distal left main coronary artery aneurysm presenting as non-ST-elevation myocardial infarction: surgical vs. medical strategy in two cases-a case report. [PDF]
Eur Heart J Case RepBalsak HI +4 more
europepmc +1 more source
Prospective randomised double‐blind trial: holmium laser lithotripsy with vs without Moses™ 2.0
BJU International, EarlyView.Objective To assess the effect of Moses™ 2.0 (Lumenis Be Ltd., Yokneam Illit, Israel; Boston Scientific, Marlborough, MA, USA) for lithotripsy of renal stones of 8–20 mm in diameter on operative time, surgeon workload, and retropulsion. Subjects/Patients and Methods In our multicentre, randomised, double‐blind clinical trial, patients were randomised 1:
Kimberly A. Maciolek +19 more
wiley +1 more source
Concurrent Diabetic Ketoacidosis and Non-ST-Elevation Myocardial Infarction: A Complex Cardiometabolic Emergency. [PDF]
CureusMoin K, Amini Z, Umar R.
europepmc +1 more source
Non‐canonical PKG1 regulation in cardiovascular health and disease
British Journal of Pharmacology, EarlyView.It is well established that the cyclic GMP‐dependent protein kinase I (PKG1) is canonically activated by cyclic guanosine monophosphate (cGMP), enabling its regulation of vascular tone, cardiac function and smooth muscle homeostasis. However, diverse non‐canonical stimuli of PKG1 have also been identified.
Jie Su, Joseph Robert Burgoyne
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Frailty first: Rethinking invasive strategies for elderly patients with non-ST-elevation myocardial infarction. [PDF]
World J CardiolMilaras N, Toutouzas K, Sideris S.
europepmc +1 more source
Novel therapeutic targets for chronic visceral pain in gastrointestinal disorders
British Journal of Pharmacology, EarlyView.Chronic visceral pain imposes a major clinical challenge in gastroenterology and beyond, profoundly impacting patients' quality of life. However, limited understanding of its complex, multifaceted pathophysiology, encompassing both peripheral and central mechanisms, continues to impede the development of effective management strategies.
Fleur Veldman +3 more
wiley +1 more source
Assessment of the Effectiveness of Early Versus Delayed Invasive Strategies in Non-ST Elevation Myocardial Infarction (NSTEMI): A Systematic Review and Meta-Analysis. [PDF]
CureusKamble A +5 more
europepmc +1 more source
Cardiovascular toxicity from immune checkpoint inhibitor therapy: an inflammatory continuum
British Journal of Pharmacology, EarlyView.Immune checkpoint inhibitor (ICI) therapy has markedly improved outcomes in advanced malignancies but has also revealed a distinct spectrum of cardiovascular immune‐related adverse events. Myocarditis represents the most severe manifestation, while non‐inflammatory left ventricular dysfunction and vascular inflammation have emerged as additional ...
Fabrice Reyes +7 more
wiley +1 more source