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Chapter 18. Non-steroidal Anti-inflammatory Agents
1975Publisher Summary The complex nature of the inflammatory diseases accentuates the difficulty of studying the mechanism of action of anti-inflammatory agents. It has been speculated that non-steroidal antiinflammatory agents (NAA's) may exert their effects by inhibiting leucocyte migration inhibiting prostaglandin synthesis interfering with ...
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Effects of flunoxaprofen, a non-steroidal anti-inflammatory agent, on the cardiovascular system.
Journal of medicine, 1992The effects of flunoxaprofen (FL) were investigated using anesthetized normotensive and spontaneously hypertensive (SHR) young and old rats. The animals were divided into two groups. One group received a non-steroidal anti-inflammatory agent at doses significantly inhibiting prostaglandin (PG)-cyclooxygenase; the other received no non-steroidal anti ...
ROSSI, Francesco+4 more
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Pharmacology and comparative toxicology of non-steroidal anti-inflammatory agents
1983Non-steroidal anti-inflammatory agents (NSAIA) are widely used drugs in human therapy and to a lesser extent in veterinary practice. They belong to many chemical classes (although most of them are organic acids) and have in common antipyretic, analgesic and anti-inflammatory activity.
G. Mazue, J. Berthe, P. Richez
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HPLC Analysis of Anti-Inflammatory Agents (Non-Steroidal and Steroidal)
1988AI* agents in biological fluids are commonly analyzed chromatographically, maybe by GC but usually by HPLC — typically RP — with UV detection (sometimes fluorescence or EC). HPLC is also convenient in percutaneous absorption studies on AI agents in gels and creams. Solvent extraction is often not necessary if the drug concentration, e.g.
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