Results 41 to 50 of about 152,017 (383)

Bright spots in the darkness of cancer: A review of starfishes-derived compounds and their anti-tumor action [PDF]

, 2019
The fight against cancer represents a great challenge for researchers and, for this reason, the search for new promising drugs to improve cancer treatments has become inevitable.
Arizza V., Lazzara V., Luparello C., Mauro M., Vazzana M.   +4 more
core   +1 more source

Use of gastroprotective agents in recommended doses in hospitalized patients receiving NSAIDs: a drug utilization study [PDF]

, 2006
OBJECTIVE: In recent years, studies investigated to what extend recommendations for co-prescribing gastroprotective agents in prevention of NSAID-induced gastrointestinal complications are followed in clinical practice.
Bilušić, Marinko, Erdeljić, Viktorija, Francetić, Igor, Huić, Mirjana, Macolić Šarinić, Viola, Makar-Aušperger, Ksenija, Merčep, Iveta   +6 more
core   +1 more source

Toward Multitasking Pharmacological COX-Targeting Agents: Non-Steroidal Anti-Inflammatory Prodrugs with Antiproliferative Effects

Molecules, 2021
The antitumor activity of certain anti-inflammatory drugs is often attributed to an indirect effect based on the inhibition of COX enzymes. In the case of anti-inflammatory prodrugs, this property could be attributed to the parent molecules with ...
Fedora Grande, Francesca Giordano, Maria Antonietta Occhiuzzi, Carmine Rocca, Giuseppina Ioele, Michele De Luca, Gaetano Ragno, Maria Luisa Panno, Bruno Rizzuti, Antonio Garofalo   +9 more
doaj   +1 more source

Treatment recommendations for psoriatic arthritis [PDF]

, 2008
Objective: To develop comprehensive recommendations for the treatment of the various clinical manifestations of psoriatic arthritis (PsA) based on evidence obtained from a systematic review of the literature and from consensus opinion.
Boehncke, Wolf-Henning, Fiorentino, David, FitzGerald, Oliver, Gladman, Dafna D., Gottlieb, Alice B., Helliwell, Philip, Kavanaugh, Arthur, McHugh, Neil J., Mease, Philip J., Nash, Peter, Qureshi, Abrar A., Ritchlin, Christopher T., Soriano, Enrique R., Taylor, William J., Vlam, Kurt de   +14 more
core   +3 more sources

Gastroprotective effects of oral nucleotide administration [PDF]

, 2006
BACKGROUND AND AIMS: Nucleotides form the building blocks of DNA and are marketed as dietary supplements, alone or in combination with other ingredients, to promote general health.
Belo, A, Fitzgerald, A, Ghosh, S, Marchbank, T, Playford, RJ   +4 more
core   +2 more sources

Nonsteroidal anti-inflammatory therapy: changes on renal function of healthy dogs [PDF]

Acta Cirúrgica Brasileira, 2013
PURPOSE: To evaluate the renal function in healthy dogs submitted to nonselective and preferential COX-2 nonsteroidal anti-inflammatory drug (NSAID) therapy.
Marina Borges, Rivaldo Marini Filho, Cecília Braga Laposy, Priscylla Tatiana Chalfun Guimarães-Okamoto, Marina Platzeck Chaves, André Nanny Le Sueur Vieira, Alessandra Melchert   +6 more
doaj   +1 more source

Celecoxib to improve scar quality following acute burn injury: Lessons learned after premature termination of a randomised trial

Burns Open
Background: Pre-clinical studies suggest that non-steroidal anti-inflammatory therapy may reduce acute inflammation and modulate scar formation after burn injury.
Edward Raby, Paul Gittings, Edward Litton, Aaron Berghuber, Dale Wesley Edgar, Jo Camilleri, Kris Owen, Rosemary Kendell, Laurens Manning, Mark Fear, Fiona Melanie Wood   +10 more
doaj   +1 more source

Aspirin and other non-steroidal anti-inflammatory drugs and depression, anxiety, and stress-related disorders following a cancer diagnosis: a nationwide register-based cohort study

BMC Medicine, 2020
Background Cancer patients have a highly increased risk of psychiatric disorders following diagnosis, compared with cancer-free individuals. Inflammation is involved in the development of both cancer and psychiatric disorders.
Kejia Hu, Arvid Sjölander, Donghao Lu, Adam K. Walker, Erica K. Sloan, Katja Fall, Unnur Valdimarsdóttir, Per Hall, Karin E. Smedby, Fang Fang   +9 more
doaj   +1 more source

Prodrug Approach: NSAID Conjugates of Platinum Compounds as Anti-Cancer Agents

Iraqi Journal of Pharmaceutical Sciences, 2023
Prodrug based synthetic approach is a very promising area of research to enhance the pharmaco–kinetic and pharmaco-dynamic properties of the drugs with the remarkable reduction of the side effects.
NIJA B
doaj   +1 more source

Non-steroidal anti-inflammatory drugs—changes in prescribing may be warranted [PDF]

, 2006
No abstract ...
Madhok, R., McKellar, G., Singh, G., Wu, O.   +3 more
core   +1 more source