Results 41 to 50 of about 142,547 (224)

Antitubercular specific activity of ibuprofen and the other 2-arylpropanoic acids using the HT-SPOTi whole-cell phenotypic assay [PDF]

, 2013
Objectives: Lead antituberculosis (anti-TB) molecules with novel mechanisms of action are urgently required to fuel the anti-TB drug discovery pipeline.
Bhakta, Sanjib, Birchall, K., Evangelopoulos, Dimitrios, Gibbons, S., Gupta, Antima, Guzman, Juan D., Malkinson, J., McHugh, T.D., Mwaigwisya, S., Saxty, B.   +9 more
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Cancer and systemic inflammation: treat the tumour and treat the host [PDF]

, 2014
Determinants of cancer progression and survival are multifactorial and host responses are increasingly appreciated to have a major role. Indeed, the development and maintenance of a systemic inflammatory response has been consistently observed to confer ...
BJ Laird, BJ Laird, BJ Laird, C Gabay, C Madeddu, C S D Roxburgh, CS Roxburgh, D C McMillan, D Hanahan, DC McMillan, DC McMillan, DC McMillan, DC McMillan, GJ Guthrie, J Illi, J Kirkova, JS Temel, K Lundholm, K Ng, LN Saligan, M Kacevska, M Trajkovic-Vidakovic, MJ Proctor, MK Jain, N MacDonald, PM Ridker, R Dantzer, S Yennurajalingam, T Christoffersen, TS Solheim, X Liao   +30 more
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Topical diclofenac: Clinical effectiveness and current uses in osteoarthritis of the knee and soft tissue injuries [PDF]

, 2008
Background: Diclofenac is a commonly used non-steroidal anti-inflammatory drug (NSAID) for symptom control in osteoarthritis (OA) of the knee and soft tissue injuries.
Banning, M
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Choosing and using non-steroidal anti-inflammatory drugs in haemophilia [PDF]

, 2016
The management of pain and inflammation in haemophilic arthropathy is challenging due to the lack of anti-inflammatory analgesic agents perfectly suitable for this population.
Baigent, Biere-Rafi, Braden, Brown, Button, Cagnoni, Caldwell, Castellsague, Chen, Crofford, Curhan, Daly, de Abajo, Dolan, Dworzynski, Eyster, FitzGerald, Forbes, Forman, Fransen van de Putte, Garcia-Poza, Gisbert, Gonzalez-Perez, Grosser, Hallas, Harirforoosh, Hawkey, Hinz, Holstein, Huerta, Hunt, Hunt, Huntjens, Inwood, Jansen, Kamphuisen, Kearney, Konkle, Kulkarni, Kulkarni, Laine, Lanas, Lanas, Lanza, Lin, Makris, Mannucci, Masso Gonzalez, McGettigan, Mittal, Odom, Ofman, Papatheodoridis, Park, Patrignani, Pergantou, Rattray, Riley, Rostom, Scarpignato, Scarpignato, Scarpignato, Schulman, Segasothy, Segasothy, Solomon, Soucie, Srivastava, Stephensen, Steven, Trelle, Tuskey, Van, White, Yeomans, Young   +75 more
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Health-related quality of life and depression among participants in the Sjögren's International Collaborative Clinical Alliance registry. [PDF]

, 2017
ObjectiveTo examine health-related quality of life (HRQoL) and depression among participants in an international Sjögren's syndrome (SS) registry, comparing those with and without SS.MethodsCross-sectional study of participants in the Sjögren's ...
Chou, Annie, Criswell, Lindsey A, Daniels, Troy E, Gonzales, John A, Shiboski, Caroline H, Shiboski, Stephen C   +5 more
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Arzanol, a prenylated heterodimeric phloroglucinyl pyrone, inhibits eicosanoid biosynthesis and exhibits anti-inflammatory efficacy in vivo. [PDF]

, 2011
Based on its capacity to inhibit in vitro HIV-1 replication in T cells and the release of pro-inflammatory cytokines in monocytes, the prenylated heterodimeric phloroglucinyl α-pyrone arzanol was identified as the major anti-inflammatory and anti-viral ...
Appendino G, Bauer J, Dehm F, Koeberle A, Northoff H, Pollastro F, ROSSI, ANTONIETTA, SAUTEBIN, LIDIA, Werz O.   +8 more
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Chemoprevention of Gastric Cancer: Non-steroidal Anti-inflammatory Drugs Including Aspirin

The Korean Journal of Helicobacter and Upper Gastrointestinal Research, 2017
Many reports have been published that provide epidemiological evidence supporting the efficacy of aspirin and non-steroidal anti-inflammatory drugs (NSAIDs) in cancer prevention.
Kee Don Choi
doaj   +1 more source

Celecoxib exerts protective effects in the vascular endothelium via COX-2-independent activation of AMPK-CREB-Nrf2 signalling [PDF]

, 2018
Although concern remains about the athero-thrombotic risk posed by cyclo-oxygenase (COX)-2-selective inhibitors, recent data implicates rofecoxib, while celecoxib appears equivalent to NSAIDs naproxen and ibuprofen.
A Arfe, A Bauer, A Kardosh, A Salminen, AJ Shaywitz, B Fisslthaler, BR Gunter, C Liu, C Mo, C Patrono, CC Thornton, CH He, D Carling, DH Solomon, DM Thomson, EH Kobayashi, EL Fosbol, FY Li, H Mylroie, HP Lin, HT Cheng, I Tegeder, IE Schauer, J Lindhardsen, J Steffel, JA Mitchell, JM Cacicedo, JS Wang, K Iwasaki, K Zimmermann, LC Wu, ME Widlansky, MP Seldon, MP Soares, MT Nurmohamed, N Bhala, NJ Goodson, NM Davies, NM Davies, P Kale, PA Watson, R Chenevard, R Gozzelino, RS Bresalier, S Jacob, S Trelle, SE Nissen, SK Paulson, SK Paulson, SL Colombo, SS Hamdulay, SS Hamdulay, SW Ryter, TD Penning, TM MacDonald, VL King, WB White, X Liu, XM Liu, Y Hattori, ZQ Zou   +60 more
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Advent of Novel Phosphatidylcholine-Associated Nonsteroidal Anti-Inflammatory Drugs with Improved Gastrointestinal Safety

Gut and Liver, 2013
The mucosa of the gastrointestinal (GI) tract exhibits hydrophobic, nonwettable properties that protect the underlying epithelium from gastric acid and other luminal toxins.
doaj   +1 more source

Recent Therapeutics Policies of Arthritis Rheumatoid (Part I) [PDF]

, 2018
Therapy in RA has undergone many advances today and in line with knowledge of the pathogenesis of RA, the current therapeutic goal is to alter the journey and control the activity of RA disease.
Andisari, H. E. (Hendrata)
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