Results 141 to 150 of about 478,729 (278)

Trademark protection or protectionism? [PDF]

This paper explores the extent to which discrimination against foreign applicants in the trademark registration process can be used as a"behind-the-border"barrier to imports.
Baroncelli, Eugenia, Krivonos, Ekaterina, Olarreaga, Marcelo   +2 more
core  

Engineering Osteoimmune Responses with Functionalized Orthopedic Implants for Post‐Operative Osteosarcoma Treatment

Advanced Science, EarlyView.
Osteosarcoma is the most common primary bone tumor with limited treatment options and a terrible prognosis. This review provides a comprehensive summary of the recent development of osteoimmunomodulatory implants for post‐operative osteosarcoma treatment, of which the potential utility in evoking durable anti‐osteosarcoma immunity and accelerating bone
Yilong Dong, Lingshuang Wang, Hui Zhang, Menghuan Li, Zhong Luo, Yan Hu, Chunyuan Cai   +6 more
wiley   +1 more source

Methods to evaluate the performance of a multicomponent meningococcal serogroup B vaccine. [PDF]

mSphere
Borrow R, Tomasi Cont L, Toneatto D, Bambini S, Bobde S, Sohn W-Y, Biolchi A, Masignani V, Beernink PT, Lattanzi M.   +9 more
europepmc   +1 more source

Developing a Single‐Cell Spatial Transcriptomics Workflow for In Vivo Evaluation of Implanted Biomaterials

Advanced Science, EarlyView.
This work establishes a standardized, high‐resolution spatial transcriptomics workflow for characterizing host responses to biomaterial implants. Using the 10× Xenium platform, the pipeline integrates spatial mapping, subclustering, and functional enrichment to resolve immune and stromal cell organization at single‐cell resolution, enabling ...
Alex H.P. Chan, Yunfei Hu, Billie Pardavi, Xueying Xu, Angus J. Grant, Steven G. Wise, Lipin Loo, Richard P. Tan   +7 more
wiley   +1 more source

The EAES intellectual property protection guide. [PDF]

Surg Endosc
Nakajima K, Manfredi L, Yoshida E, Horeman T, Mintz Y.   +4 more
europepmc   +1 more source

“Catchy Phrases that Convey a Message”: The Danger of Tam’s Copymark Creep and Trademark Law’s New First Amendment Analysis

, 2020
Lantagne, Stacey M.
core  

U.S. Supreme Court Surveys: 2016 Term. Matal v. Tam: Free Speech Meets Disparaging Trademarks in the Supreme Court [PDF]

, 2018
Kuckes, Niki
core   +2 more sources

Fibrates Inhibit PLTP‐induced M2 Macrophage Infiltration and Increase the Sensitivity of Hepatocellular Carcinoma to ICIs

Advanced Science, EarlyView.
Phospholipid transfer protein(PLTP) plays a critical role in forming a complex with kinase A (AURKA) and P65. This interaction facilitates phosphorylation of P65 at Ser536, leading to the activation of the NF‐κB signaling pathway. Ultimately, this leads to the upregulation of downstream cytokines, including IL‐6, IL‐8, and CSF‐1, which promotes M2 ...
Xinyue Liang, Yaning Li, Jianxun Cai, Lisi Luo, Pengfei Yang, Yutong Chen, Jiancong Zhou, Yan Zeng, Jiaping Yu, Weiyu Zhang, Wenzheng Pang, Yufang Li, Chunhua Wen, Jian Li, Linjuan Zeng   +14 more
wiley   +1 more source

User-Centered Redesign of Monitoring Alarms: A Pre-Post Study on Perception, Functionality, and Recognizability Following Real-Life Clinical Implementation. [PDF]

Healthcare (Basel)
Hunn C, Nöthiger CB, Braun J, Sen Y, Sen A, Akbas S, Hoffmann M, Neumann E, Gasciauskaite G, Tscholl DW, Roche TR.   +10 more
europepmc   +1 more source

Telomere‐to‐Telomere Genomes Reveal that Multiscale Evolution Shapes the Largest Metabolic Arsenal of Diaporthe Fungi

Advanced Science, EarlyView.
This study presents the first telomere‐to‐telomere genomes and population resources for Diaporthe pathogens, uncovering the largest known fungal repertoire of secondary metabolite gene clusters. Structural variations and horizontal gene transfer drive cluster diversification, while specific rapidly evolving clusters control virulence, offering novel ...
Kainan Li, Chen Zhang, Zhichao Zhang, Jiaheng Cheng, Qiuyan Gao, Long Gao, Xiaolin Zhao, Wei Yan, Yuanchao Wang, Wenwu Ye   +9 more
wiley   +1 more source