Results 21 to 30 of about 20,899 (267)
Modern management of acute non-variceal upper gastrointestinal bleeding [PDF]
Postgraduate Medical Journal, 2013 Abstract An acute upper gastrointestinal bleed (AUGIB) often represents a life-threatening event and is recognised universally as a common cause of emergency hospitalisation. Large observational studies have improved our understanding of the disease characteristics and its impact on mortality but despite significant advancement in ...
Vinod S. Hegade +3 more
openalex +3 more sources
Hepatology, EarlyView., 2022 A deleterious variant of FCHSD1 results in mTOR pathway overactivation and may cause porto‐sinusoidal vascular disorder (PSVD). The pedigree of the family demonstrated an autosomal dominant disease with variable expressivity. Whole‐genome sequencing and Sanger sequencing both validated the existence of the FCHSD1 variant and the heterozygosity of c ...
Jingxuan Shan +19 more
wiley +1 more source
Health disparities in chronic liver disease
Hepatology, EarlyView., 2022 Abstract The syndemic of hazardous alcohol consumption, opioid use, and obesity has led to important changes in liver disease epidemiology that have exacerbated health disparities. Health disparities occur when plausibly avoidable health differences are experienced by socially disadvantaged populations.
Ani Kardashian +3 more
wiley +1 more source
Management of portal hypertensive gastropathy and other bleeding [PDF]
Clinical and Molecular Hepatology, 2014 A major cause of cirrhosis related morbidity and mortality is the development of variceal bleeding, a direct consequence of portal hypertension. Less common causes of gastrointestinal bleeding are peptic ulcers, malignancy, angiodysplasia, etc.
Woo Jin Chung
doaj +1 more source
Janus kinase 2 inhibition by pacritinib as potential therapeutic target for liver fibrosis
Hepatology, EarlyView., 2022 Diagram of the activation of the profibrotic and procontractile Janus kinase 2 (JAK2)/Ras homolog family member A/Rho‐kinase pathway and the inhibition of phosphorylated JAK2 by pacritinib to inhibit hepatic stellate cell activity. Abstract Background and Aims Janus kinase 2 (JAK2) signaling is increased in human and experimental liver fibrosis with ...
Sandra Torres +21 more
wiley +1 more source
Annals of Hepatology, 2022 Introduction and Objectives: Liver cirrhosis is a highly prevalent worldwide disease and in the last decade, there has been an increase of 13%. Patients with advanced liver disease are at higher risk of developing life-threatening decompensations; one of
I.E. Bravo-Espinoza +6 more
doaj +1 more source
Seasonal Impacts on the Incidence of Esophageal Variceal Hemorrhage: A Nationwide Analysis across a Decade [PDF]
Clinical Endoscopy, 2020 Background/Aims Seasonal variation has previously been reported in relation to the incidence of non-variceal upper gastrointestinal bleeding; however, the impact of seasonal variation on variceal bleeding is not known.
Mohamed Tausif Siddiqui +5 more
doaj +1 more source
Management of Non-Variceal Upper Gastrointestinal Bleeding [PDF]
Clinical Endoscopy, 2012 Upper gastrointestinal bleeding (UGIB) is a critical condition that demands a quick and effective medical management. Non-variceal UGIB, especially peptic ulcer bleeding is the most significant cause. Appropriate assessment and treatment have a major influence on the prognosis of patients with UGIB.
Kim, Seung Young +3 more
openaire +2 more sources
The Indonesian Journal of Gastroenterology, Hepatology and Digestive Endoscopy, 2020 Upper gastrointestinal bleeding is differentiated based on clinical needs into variceal and non-variceal bleeding. The cause of varices bleeding is portal hypertension, both cirrhosis and non-cirrhosis. Gastric varices occur less than esophageal varices,
Jualita Heidy Saputri, Budi Widodo
doaj +1 more source
Endoscopic clipping in non-variceal upper gastrointestinal bleeding treatment
Clinical Endoscopy, 2022 Since the earliest reports, advanced clipping systems have been developed, and it is possible to choose among many models with different structural and technical features. The main drawback of through-the-scope clips is their small size, which allows the compression of limited amounts of tissue needed for large-size vessel treatment.
Giuseppe Galloro +8 more
openaire +4 more sources